Results 11 to 20 of about 87,270,183 (304)

Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives [PDF]

open access: yesCancer Management and Research, 2014
Antonio Díaz-López,1 Gema Moreno-Bueno,1,2 Amparo Cano11Departamento de Bioquímica, Facultad de Medicina, Universidad Autónoma de Madrid, Instituto de Investigaciones Biomédicas “Alberto Sols” (CSIC-UAM ...
Díaz-López A   +2 more
doaj   +2 more sources

Epithelial-to-Mesenchymal Transition in Pancreatic Adenocarcinoma

open access: yesThe Scientific World Journal, 2010
Epithelial to mesenchymal transition (EMT) is a physiologic process that allows morphological and genetic changes of carcinoma cells from an epithelial to a mesenchymal phenotype, which is the basis of the high metastatic potential of pancreatic cancer ...
Carla Cano   +2 more
doaj   +3 more sources

Mechanochemical alterations in lung cells during fibrogenesis [PDF]

open access: yes, 2009
Màster en BiofísicaIdiopath pulmonary fibrosis (IPF) is a usually fatal disease associated with hardening of the lung tissue, epithelial injury and abnormal wound healing.
Pavelescu, Irina
core   +6 more sources

Epithelial‐to‐mesenchymal transitions in the liver† [PDF]

open access: yesHepatology, 2009
The outcome of liver injury is dictated by the effectiveness of repair. Successful repair (i.e., regeneration) results in replacement of dead epithelial cells with healthy epithelial cells, and reconstructs normal hepatic structure and function. Liver regeneration is known to involve replication of surviving mature hepatocytes and bile duct cells. This
Steve S, Choi, Anna Mae, Diehl
openaire   +2 more sources

Vitamin D and the Epithelial to Mesenchymal Transition [PDF]

open access: yesStem Cells International, 2016
Several studies support reciprocal regulation between the active vitamin D derivative 1α,25‐dihydroxyvitamin D3 (1,25(OH)2D3) and the epithelial to mesenchymal transition (EMT). Thus, 1,25(OH)2D3 inhibits EMT via the induction of a variety of target genes that encode cell adhesion and polarity proteins responsible for the epithelial phenotype and ...
Larriba, María Jesús   +2 more
openaire   +5 more sources

Arginine methylation in the epithelial‐to‐mesenchymal transition [PDF]

open access: yesThe FEBS Journal, 2021
Epithelial cells acquire mesenchymal characteristics during embryonic development, wound healing, fibrosis, and in cancer in a processed termed epithelial‐to‐mesenchymal transition (EMT). Regulatory networks of EMT are controlled by post‐transcriptional, translational, and post‐translational mechanisms, in which arginine methylation is critically ...
Jian Qin, Jian Xu
openaire   +2 more sources

TGF-beta 1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy [PDF]

open access: yes, 2010
Background/Aims: Epithelial-to-mesenchymal cell transformation (EMT) is the trans-differentiation of tubular epithelial cells into myofibroblasts, an event underlying progressive chronic kidney disease in diabetes, resulting in fibrosis.
Hills, Claire E., Squires, Paul E.
core   +1 more source

The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy [PDF]

open access: yes, 2011
Transforming Growth Factor-beta (TGF-β) is a pro-sclerotic cytokine widely associated with the development of fibrosis in diabetic nephropathy. Central to the underlying pathology of tubulointerstitial fibrosis is epithelial-to-mesenchymal transition ...
Hills, Claire E.   +3 more
core   +1 more source

The Epithelial-to-Mesenchymal Transition in Cancer [PDF]

open access: yesCancers, 2018
The epithelial-to-mesenchymal transition (EMT) occurs during normal embryonic development, tissue regeneration, organ fibrosis, and wound healing.[...]
openaire   +2 more sources

Regulation of the Epithelial to Mesenchymal Transition in Osteosarcoma

open access: yesBiomolecules, 2023
The epithelial to mesenchymal transition (EMT) is a cellular process that has been linked to the promotion of aggressive cellular features in many cancer types. It is characterized by the loss of the epithelial cell phenotype and a shift to a more mesenchymal phenotype and is accompanied by an associated change in cell markers.
Kristin Hinton   +3 more
openaire   +3 more sources

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