Results 21 to 30 of about 207,488 (262)

Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies [PDF]

Romanian Medical Journal, 2022
In the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising ...
Irina Balescu, Nicoale Bacalbasa, Iulian Brezean, Claudia Stoica, Cezar Laurentiu Tomescu, Cristina Martac, Andrei Voichitoiu, Bogdan Gaspar   +7 more
doaj   +1 more source

Epithelial to mesenchymal transition and breast cancer [PDF]

Breast Cancer Research, 2009
Epithelial-mesenchymal plasticity in breast carcinoma encompasses the phenotypic spectrum whereby epithelial carcinoma cells within a primary tumor acquire mesenchymal features and re-epithelialize to form a cohesive secondary mass at a metastatic site.
Tomaskovic-Crook, Eva, Thompson, Rik, Thiery, Paul   +2 more
openaire   +3 more sources

H19 Functions as a Competing Endogenous RNA to Regulate EMT by Sponging miR-130a-3p in Glioma

Cellular Physiology and Biochemistry, 2018
Background/Aims: Glioma is one of the most devasting tumors and confers dismal prognosis. Long noncoding RNAs(lncRNAs) have emerged as important regulators in various tumors including glioma. A classic lncRNA-H19, which is found to be highly expressed in
Qi Hu, Jianxing Yin, Ailiang Zeng, Xin Jin, Zhuoran Zhang, Wei Yan, Yongping You   +6 more
doaj   +1 more source

Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles. [PDF]

PLoS ONE, 2016
Mesenchymal-epithelial interactions play an important role in renal tubular morphogenesis and in maintaining the structure of the kidney. The aim of this study was to investigate whether extracellular vesicles (EVs) produced by human renal proximal ...
Giulia Chiabotto, Stefania Bruno, Federica Collino, Giovanni Camussi   +3 more
doaj   +1 more source

High expression of forkhead box protein C2 is associated with aggressive phenotypes and poor prognosis in clinical hepatocellular carcinoma

BMC Cancer, 2018
Background Hepatocellular carcinoma (HCC) is one of the major causes of tumor death; thus, the identification of markers related to its diagnosis and prognosis is critical. Previous studies have revealed that epithelial-to-mesenchymal transition (EMT) is
Yuki Shimoda, Yasunari Ubukata, Tadashi Handa, Takehiko Yokobori, Takayoshi Watanabe, Dolgormaa Gantumur, Kei Hagiwara, Takahiro Yamanaka, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Norifumi Harimoto, Ayaka Katayama, Toshiaki Hikino, Takaaki Sano, Kyoichi Ogata, Hiroyuki Kuwano, Ken Shirabe, Tetsunari Oyama   +20 more
doaj   +1 more source

Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar   +5 more
doaj   +1 more source

The Role of Histone Variants in the Epithelial-To-Mesenchymal Transition [PDF]

Cells, 2020
The epithelial-to-mesenchymal transition (EMT) is a physiological process activated during early embryogenesis, which continues to shape tissues and organs later on. It is also hijacked by tumor cells during metastasis. The regulation of EMT has been the focus of many research groups culminating in the last few years and resulting in an elaborate ...
Hamiche, Ali, Lone, Imtiaz Nisar, Sengez, Burcu, Dimitrov, Stefan, Alotaibi, Hani   +4 more
openaire   +6 more sources

Hepatic regeneration and the epithelial to mesenchymal transition [PDF]

World Journal of Gastroenterology, 2013
Liver injuries are repaired by fibrosis and regeneration. The core stage is the repair response and fibrosis formation as a scar. The cause of overly-responsive scar formation and diminished regeneration, especially in liver fibrosis and cirrhosis, is still unknown.
Xue, Zeng-Fu, Wu, Xiu-Min, Liu, Ming
openaire   +3 more sources

The Epithelial-to-Mesenchymal Transition in Development and Cancer [PDF]

Annual Review of Cancer Biology, 2020
Epithelial-to-mesenchymal transitions (EMTs) are complex cellular processes where cells undergo dramatic changes in signaling, transcriptional programming, and cell shape, while directing the exit of cells from the epithelium and promoting migratory properties of the resulting mesenchyme.
Alexandre, Francou, Kathryn V, Anderson
openaire   +2 more sources

Epithelial mesenchymal transition in human menstruation and implantation

Endocrine Journal
The endometrium during the sexual cycle undergoes detachment, tissue remodeling, and differentiation during the menstrual cycle. Localized and transient destruction and regeneration of endometrial tissue are also essential for pregnancy.
Hiroshi Uchida
doaj   +1 more source