Results 31 to 40 of about 87,270,183 (304)

Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles. [PDF]

PLoS ONE, 2016
Mesenchymal-epithelial interactions play an important role in renal tubular morphogenesis and in maintaining the structure of the kidney. The aim of this study was to investigate whether extracellular vesicles (EVs) produced by human renal proximal ...
Giulia Chiabotto, Stefania Bruno, Federica Collino, Giovanni Camussi   +3 more
doaj   +1 more source

High expression of forkhead box protein C2 is associated with aggressive phenotypes and poor prognosis in clinical hepatocellular carcinoma

BMC Cancer, 2018
Background Hepatocellular carcinoma (HCC) is one of the major causes of tumor death; thus, the identification of markers related to its diagnosis and prognosis is critical. Previous studies have revealed that epithelial-to-mesenchymal transition (EMT) is
Yuki Shimoda, Yasunari Ubukata, Tadashi Handa, Takehiko Yokobori, Takayoshi Watanabe, Dolgormaa Gantumur, Kei Hagiwara, Takahiro Yamanaka, Mariko Tsukagoshi, Takamichi Igarashi, Akira Watanabe, Norio Kubo, Kenichiro Araki, Norifumi Harimoto, Ayaka Katayama, Toshiaki Hikino, Takaaki Sano, Kyoichi Ogata, Hiroyuki Kuwano, Ken Shirabe, Tetsunari Oyama   +20 more
doaj   +1 more source

Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar   +5 more
doaj   +1 more source

MicroRNA Regulation of Epithelial to Mesenchymal Transition [PDF]

Journal of Clinical Medicine, 2016
Epithelial to mesenchymal transition (EMT) is a central regulatory program that is similar in many aspects to several steps of embryonic morphogenesis. In addition to its physiological role in tissue repair and wound healing, EMT contributes to chemo resistance, metastatic dissemination and fibrosis, amongst others.
Mohammed Abba, Nitin Patil, Jörg Leupold, Heike Allgayer   +3 more
openaire   +2 more sources

Epithelial to Mesenchymal Transition in a Clinical Perspective [PDF]

Journal of Oncology, 2015
Tumor growth and metastatic dissemination rely on cellular plasticity. Among the different phenotypes acquired by cancer cells, epithelial to mesenchymal transition (EMT) has been extensively illustrated. Indeed, this transition allows an epithelial polarized cell to acquire a more mesenchymal phenotype with increased mobility and invasiveness.
Jennifer Pasquier, Nadine Abu-Kaoud, Haya Al Thani, Arash Rafii   +3 more
openaire   +3 more sources

The Role of Histone Variants in the Epithelial-To-Mesenchymal Transition [PDF]

Cells, 2020
The epithelial-to-mesenchymal transition (EMT) is a physiological process activated during early embryogenesis, which continues to shape tissues and organs later on. It is also hijacked by tumor cells during metastasis. The regulation of EMT has been the focus of many research groups culminating in the last few years and resulting in an elaborate ...
Hamiche, Ali, Lone, Imtiaz Nisar, Sengez, Burcu, Dimitrov, Stefan, Alotaibi, Hani   +4 more
openaire   +6 more sources

Epithelial mesenchymal transition in human menstruation and implantation

Endocrine Journal
The endometrium during the sexual cycle undergoes detachment, tissue remodeling, and differentiation during the menstrual cycle. Localized and transient destruction and regeneration of endometrial tissue are also essential for pregnancy.
Hiroshi Uchida
doaj   +1 more source

The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma [PDF]

, 2012
Background: Epithelial-to-mesenchymal transition (EMT) has recently been implicated in the initiation and progression of renal cell carcinoma (RCC). Some mRNA gene expression studies have suggested a link between the EMT phenotype and poorer clinical ...
Antony C P Riddick, Stewart Grant D., Faratian Dana, Theodoulou Marianna, Grant D Stewart, Dana Faratian (171110), O'Mahony Fiach C., O'Mahony, Fiach C, James Varley (181899), David J. Harrison (171106), Jyoti Nanda (181902), Riddick, Antony C P, Varley James, Marianna Theodoulou, Dana Faratian, Varley, James, Riddick Antony C. P., Harrison David J., Fiach C O'Mahony, Antony C. P. Riddick (145315), Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Faratian, Dana, Riddick, Antony C. P., Nanda Jyoti, Marianna Theodoulou (181905), Grant D. Stewart (145312), Theodoulou, Marianna, Nanda, Jyoti, Stewart, Grant D., James Varley, Stewart, Grant D, Fiach C. O'Mahony (181892), Harrison, David J.   +35 more
core   +3 more sources

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts [PDF]

, 2010
Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner, Vafaizadeh, Vida, Groner, Bernd, Petra AB Klemmt, Vida Vafaizadeh, Klemmt, Petra A. B.   +5 more
core   +1 more source

The Epithelial-to-Mesenchymal Transition in Development and Cancer [PDF]

Annual Review of Cancer Biology, 2020
Epithelial-to-mesenchymal transitions (EMTs) are complex cellular processes where cells undergo dramatic changes in signaling, transcriptional programming, and cell shape, while directing the exit of cells from the epithelium and promoting migratory properties of the resulting mesenchyme.
Alexandre, Francou, Kathryn V, Anderson
openaire   +2 more sources