Results 51 to 60 of about 2,478,278 (345)
Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis
Nature Communications, 2020 Gut microbial dysbiosis is associated with the development of autoimmune disease, but the mechanisms by which microbial dysbiosis affects the transition from asymptomatic autoimmunity to inflammatory disease are incompletely characterized.
N. Tajik +28 more
semanticscholar +1 more source
Allergy as an epithelial barrier disease [PDF]
Clinical and Translational Allergy, 2011 AbstractThe objective of this review is to focus on putative modified epithelial functions related to allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which could be the primary defect in the pathogenesis of allergic reaction.
Mattila Pirkko +4 more
openaire +3 more sources
Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon [PDF]
, 2015 Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia.
Clara Belzer +13 more
core +2 more sources
IL-1β and the Intestinal Epithelial Tight Junction Barrier
Frontiers in Immunology, 2021 The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of contents from the intestinal lumen into the intestinal tissue and systemic circulation.
L. Kaminsky, Rana Al-Sadi, T. Ma
semanticscholar +1 more source
Cellular uptake and cell-to-cell transfer of polyelectrolyte microcapsules within a triple co-culture system representing parts of the respiratory tract [PDF]
, 2015 Polyelectrolyte multilayer microcapsules around 3.4 micrometers in diameter were added to epithelial cells, monocyte-derived macrophages, and dendritic cells in vitro and their uptake kinetics were quantified.
Fytianos, Kleanthis +5 more
core +1 more source
Surface components and metabolites of probiotics for regulation of intestinal epithelial barrier
Microbial Cell Factories, 2020 The gut microbiota can significantly affect the function of the intestinal barrier. Some intestinal probiotics (such as Lactobacillus , Bifidobacteria , a few Escherichia coli strains, and a new generation of probiotics including Bacteroides ...
Qing Liu +6 more
semanticscholar +1 more source
Animals, 2022 Simple Summary The gastrointestinal tract is a complex organization of various types of epithelial cells forming a single layer of the mucosal barrier, the host mucosal immune system, and microorganisms termed as gut microbiota inhabiting this area.
M. Gieryńska +4 more
semanticscholar +1 more source
Particle and Fibre Toxicology, 2020 Background While exposure to diesel exhaust particles has been linked to aberrant immune responses in allergic diseases such as asthma, little attention has been paid to their effects on the airway epithelial barrier.
Timothy Smyth +5 more
doaj +1 more source
Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa. [PDF]
, 2017 Previously we reported that corneal epithelial barrier function against Pseudomonas aeruginosa was MyD88-dependent. Here, we explored contributions of MyD88-dependent receptors using vital mouse eyes and confocal imaging. Uninjured IL-1R (-/-) or TLR4 (-/
Evans, David +5 more
core +3 more sources
Respiratory Research, 2023 Background Airway epithelium is the first barrier against environmental insults, and epithelial barrier dysfunction caused by cigarette smoke (CS) is particularly relevant to chronic obstructive pulmonary disease (COPD) progression.
Yun Song +8 more
doaj +1 more source