Results 31 to 40 of about 131,334 (259)
Epithelial and Neural Cadherin in Mammalian Fertilization: Studies in the Mouse Model [PDF]
Cells, 2021 Successful mammalian fertilization requires a well-orchestrated sequence of molecular events leading to gamete fusion. Since this interaction involves Ca2+-dependent adhesion events, the participation of the Ca+2-dependent cell-cell adhesion proteins Epithelial (E-cad) and Neural (N-cad) cadherin is envisaged. We have previously reported the expression
Verón, Gustavo Luis +4 more
openaire +4 more sources
CD44 upregulation in E-cadherin-negative esophageal cancers results in cell invasion. [PDF]
PLoS ONE, 2011 E-cadherin is frequently lost during epithelial-mesenchymal transition and the progression of epithelial tumorigenesis. We found a marker of epithelial-mesenchymal transition, CD44, upregulated in response to functional loss of E-cadherin in esophageal ...
Grégoire F Le Bras +5 more
doaj +1 more source
Soluble E‐cadherin: A marker of genital epithelial disruption
American Journal of Reproductive Immunology, 2022 AbstractProblemThe genital epithelial barrier is a crucial first line of defence against HIV, and epithelial disruption may enhance HIV susceptibility. Assessment of genital epithelial integrity requires biopsies, but their collection is not practical in many research settings.
Rachel Liu +10 more
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Gastrulation EMT Is Independent of P-Cadherin Downregulation. [PDF]
PLoS ONE, 2016 Epithelial-mesenchymal transition (EMT) is an evolutionarily conserved process during which cells lose epithelial characteristics and gain a migratory phenotype.
Pricila K Moly +4 more
doaj +1 more source
Cadherin and Integrin Regulation of Epithelial Cell Migration [PDF]
Langmuir, 2009 These studies quantified the relative effects of E-cadherin expression and homophilic ligation on the integrin-mediated motility of epithelial cells. Micropatterned proteins were used to quantitatively titrate the ligation of E-cadherin and integrin receptors in order to assess their coordinate influence on the migration velocities of MDA-MB-231 breast
Jonathan, Silvestre +2 more
openaire +2 more sources
Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. [PDF]
PLoS Biology, 2007 Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C.
Quynh T Phan +8 more
doaj +1 more source
CDH1 (cadherin 1, type 1, E-cadherin (epithelial)) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on CDH1 (cadherin 1, type 1, E-cadherin (epithelial)), with data on DNA, on the protein encoded, and where the gene is implicated.
MF Calmon, P Rahal
openaire +1 more source
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance
Nature Communications, 2023 E-cadherin is an essential cell‒cell adhesion protein that mediates canonical cadherin-catenin complex formation in epithelial lateral membranes.
Chao Kong +11 more
doaj +1 more source
Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent. [PDF]
PLoS ONE, 2012 Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions.
David Smyth +3 more
doaj +1 more source
Cureus, 2023 Osteosarcoma (OS) is a debilitating cancer of the bone that commonly afflicts the young and old. This may be de novo or associated with tumorigenic syndromes. However, many molecular mechanisms are still being uncovered and may offer greater avenues for screening and therapy.
Issagholian, Leo +4 more
openaire +2 more sources