Results 41 to 50 of about 131,334 (259)
Phosphatase Regenerating Liver3 and ECadherin Expression in Epithelial Ovarian Cancer
Indonesian Journal of Obstetrics and Gynecology, 2016 Objective: To determine the expression of Phosphatase Regenerating Liver-3 (PRL-3) and E-Cadherin in the epithelial ovarian cancer on various stages and differentiation grades. Method: This was a cross-sectional study design conducted at Obstetrics
Risma Maharani +2 more
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E‐cadherin: From epithelial glue to immunological regulator [PDF]
European Journal of Immunology, 2013 E‐cadherin is best known as a central molecule in adherens junctions, joining adjacent epithelial cells together, thereby safeguarding epithelial barrier function. However, recent findings have uncovered an immunological role for this adhesion molecule, linked to its expression in dendritic cells (DCs) and alternatively activated macrophages (MPHs) and
Van Den Bossche, Jan +1 more
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E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness. [PDF]
PLoS ONE, 2017 Ovarian cancer (OC) is the fifth cancer death cause in women worldwide. The malignant nature of this disease stems from its unique dissemination pattern.
Marina Rosso +16 more
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Epithelial‐cadherin Gene Is Not Mutated in Ductal Carcinomas of the Breast [PDF]
Japanese Journal of Cancer Research, 1995 We investigated mutations of the epithelial (E)‐cadherin gene and loss of heterozygosity (LOH) at flanking loci using three microsatellite markers on the long arm of chromosome 16 in 25 ductal carcinomas of the breast. Expression of E‐cadherin was also investigated immunohistochemically. No mutations were detected in exons 6 through 9 of the E‐cadherin
Kashiwaba, Masahiro +6 more
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PLoS Genetics, 2019 E-cadherin complexes with the actin cytoskeleton via cytoplasmic catenins and maintains the functional characteristics and integrity of the epithelia in normal epithelial tissues.
Adam Olson +10 more
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Interactions and Feedbacks in E-Cadherin Transcriptional Regulation
Frontiers in Cell and Developmental Biology, 2021 Epithelial tissues rely on the adhesion between participating cells to retain their integrity. The transmembrane protein E-cadherin is the major protein that mediates homophilic adhesion between neighbouring cells and is, therefore, one of the critical ...
Miguel Ramirez Moreno +2 more
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Epithelial Viscoelasticity Is Regulated by Mechanosensitive E-cadherin Turnover [PDF]
Current Biology, 2019 Studying how epithelia respond to mechanical stresses is key to understanding tissue shape changes during morphogenesis. Here, we study the viscoelastic properties of the Drosophila wing epithelium during pupal morphogenesis by quantifying mechanical stress and cell shape as a function of time.
Iyer, K. +4 more
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GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells
Cell Reports, 2019 Summary: O-GalNAc glycosylation is initiated in the Golgi by glycosyltransferases called GALNTs. Proteomic screens identified >600 O-GalNAc-modified proteins, but the biological relevance of these modifications has been difficult to determine.
Deepthi Raghu +4 more
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E-Cadherin in Pancreatic Ductal Adenocarcinoma: A Multifaceted Actor during EMT
Cells, 2020 Epithelial-to-mesenchymal transition (EMT) is a step-wise process observed in normal and tumor cells leading to a switch from epithelial to mesenchymal phenotype.
Michele Sommariva, Nicoletta Gagliano
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E‐Cadherin/β‐Catenin Complex and the Epithelial Barrier [PDF]
BioMed Research International, 2011 E‐Cadherin/β‐catenin complex plays an important role in maintaining epithelial integrity and disrupting this complex affect not only the adhesive repertoire of a cell, but also the Wnt‐signaling pathway. Aberrant expression of the complex is associated with a wide variety of human malignancies and disorders of fibrosis resulting from epithelial ...
Tian, Xinrui +8 more
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