Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells. [PDF]
Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C.
Quynh T Phan +8 more
doaj +1 more source
CDH1 (cadherin 1, type 1, E-cadherin (epithelial)) [PDF]
Review on CDH1 (cadherin 1, type 1, E-cadherin (epithelial)), with data on DNA, on the protein encoded, and where the gene is implicated.
MF Calmon, P Rahal
openaire +1 more source
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance
E-cadherin is an essential cell‒cell adhesion protein that mediates canonical cadherin-catenin complex formation in epithelial lateral membranes.
Chao Kong +11 more
doaj +1 more source
Epithelial and Neural Cadherin in Mammalian Fertilization: Studies in the Mouse Model [PDF]
Successful mammalian fertilization requires a well-orchestrated sequence of molecular events leading to gamete fusion. Since this interaction involves Ca2+-dependent adhesion events, the participation of the Ca+2-dependent cell-cell adhesion proteins Epithelial (E-cad) and Neural (N-cad) cadherin is envisaged. We have previously reported the expression
Verón, Gustavo Luis +4 more
openaire +4 more sources
Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent. [PDF]
Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions.
David Smyth +3 more
doaj +1 more source
E‐cadherin: From epithelial glue to immunological regulator [PDF]
E‐cadherin is best known as a central molecule in adherens junctions, joining adjacent epithelial cells together, thereby safeguarding epithelial barrier function. However, recent findings have uncovered an immunological role for this adhesion molecule, linked to its expression in dendritic cells (DCs) and alternatively activated macrophages (MPHs) and
Van Den Bossche, Jan +1 more
openaire +4 more sources
Phosphatase Regenerating Liver3 and ECadherin Expression in Epithelial Ovarian Cancer
Objective: To determine the expression of Phosphatase Regenerating Liver-3 (PRL-3) and E-Cadherin in the epithelial ovarian cancer on various stages and differentiation grades. Method: This was a cross-sectional study design conducted at Obstetrics
Risma Maharani +2 more
doaj +1 more source
E-cadherin: A determinant molecule associated with ovarian cancer progression, dissemination and aggressiveness. [PDF]
Ovarian cancer (OC) is the fifth cancer death cause in women worldwide. The malignant nature of this disease stems from its unique dissemination pattern.
Marina Rosso +16 more
doaj +1 more source
Epithelial‐cadherin Gene Is Not Mutated in Ductal Carcinomas of the Breast [PDF]
We investigated mutations of the epithelial (E)‐cadherin gene and loss of heterozygosity (LOH) at flanking loci using three microsatellite markers on the long arm of chromosome 16 in 25 ductal carcinomas of the breast. Expression of E‐cadherin was also investigated immunohistochemically. No mutations were detected in exons 6 through 9 of the E‐cadherin
Kashiwaba, Masahiro +6 more
openaire +2 more sources
Interactions and Feedbacks in E-Cadherin Transcriptional Regulation
Epithelial tissues rely on the adhesion between participating cells to retain their integrity. The transmembrane protein E-cadherin is the major protein that mediates homophilic adhesion between neighbouring cells and is, therefore, one of the critical ...
Miguel Ramirez Moreno +2 more
doaj +1 more source

