Results 121 to 130 of about 12,703,452 (383)

IL-37 attenuated HPV induced inflammation and growth of oral epithelial cells via regulating autophagy

Heliyon
This study investigated the impact of Human Papillomavirus (HPV) on inflammation and growth in oral epithelial cells, with a focus on the role of Interleukin-37 (IL37). Oral epithelial cells, including HOEC and HSC-3 cells, were employed in the research.
Yahong Shi, Wenjing Wang, Yunfang Bai, Xiaoying Liu, Liwei Wu, Ning Liu   +5 more
doaj   +1 more source

The epithelium of the dorsal marginal zone of Xenopus has organizer properties [PDF]

, 1992
We have investigated the properties of the epithelial layer of the dorsal marginal zone (DMZ) of the Xenopus laevis early gastrula and found that it has inductive properties similar to those of the entire Spemann organizer.
Keller, Ray, Shih, John
core  

Klebsiella pneumoniae is able to trigger epithelial-mesenchymal transition process in cultured airway epithelial cells [PDF]

, 2016
The ability of some bacterial pathogens to activate Epithelial-Mesenchymal Transition normally is a consequence of the persistence of a local chronic inflammatory response or depends on a direct interaction of the pathogens with the host epithelial cells.
A García-Fernández, A Markogiannakis, A Moustakas, AA Franco, BC Willis, C Passariello, D Kovacs, D Ranieri, Daniela Martinelli, E Candelario-Jalil, Francesca Mazzetta, G Cane, HY Kim, I Pilpilidis, I Santino, Iolanda Santino, J Martinez, JAB Strickertsson, JC Lin, JI Bàrdos, José A. Bengoechea, K Nishi, KK Kim, L Leone, LA Borthwick, Laura Leone, M Barbara, Maurizio Alimandi, ME Falagas, MH Yang, MS Wright, NS Chandel, P Chandrakesan, P Hofman, P Nordmann, R Kalluri, S De Majumdar, S Lamouille, Sabatino Valente, Salvatore Raffa, SS Leonard, SZ Ding, V Cano, Y Kondo, Y Saito, Y Yin, YT Oh   +46 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Epstein-Barr virus infection of polarized epithelial cells via the basolateral surface by memory B cell-mediated transfer infection.

PLoS Pathogens, 2011
Epstein Barr virus (EBV) exhibits a distinct tropism for both B cells and epithelial cells. The virus persists as a latent infection of memory B cells in healthy individuals, but a role for infection of normal epithelial is also likely.
Claire Shannon-Lowe, Martin Rowe
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells [PDF]

, 2001
Marina Simian, Yohei Hirai, Marc Navre, Zena Werb, André Lochter, Mina J. Bissell   +5 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Molecular Distinctions between Stasis and Telomere Attrition Senescence Barriers Shown by Long-term Culture of Normal Human Mammary Epithelial Cells [PDF]

, 2009
James C. Garbe, Sanchita Bhattacharya, Batul Merchant, Ekaterina Bassett, Karen Swisshelm, Heidi S. Feiler, Andrew J. Wyrobek, Martha R. Stampfer   +7 more
openalex   +1 more source