Results 11 to 20 of about 1,118,720 (264)

Nasal epithelial cells can act as a physiological surrogate for paediatric asthma studies. [PDF]

open access: yesPLoS ONE, 2014
INTRODUCTION: Differentiated paediatric epithelial cells can be used to study the role of epithelial cells in asthma. Nasal epithelial cells are easier to obtain and may act as a surrogate for bronchial epithelium in asthma studies.
Surendran Thavagnanam   +5 more
doaj   +1 more source

Histomorphological Characteristics and Pathological Types of Hyperproliferation of Gastric Surface Epithelial Cells

open access: yesGastroenterology Research and Practice, 2021
Objective. To investigate the histomorphological characteristics and pathological types of hyperproliferation of gastric surface epithelial cells. Methods.
Yangkun Wang   +7 more
doaj   +1 more source

Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin.

open access: yesPLoS Pathogens, 2021
Neisseria gonorrhoeae (GC) establishes infection in women from the cervix, lined with heterogeneous epithelial cells from non-polarized stratified at the ectocervix to polarized columnar at the endocervix.
Qian Yu   +4 more
doaj   +1 more source

A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

open access: yesEMBO Molecular Medicine, 2019
Therapeutic resistance is a major clinical challenge in oncology. Evidence identifies cancer stem cells (CSCs) as a driver of tumor evolution. Accordingly, the key stemness property unique to CSCs may represent a reservoir of therapeutic target to ...
Abir Arfaoui   +20 more
doaj   +1 more source

CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

open access: yesiScience, 2021
Summary: The apoptosis inducing receptor CD95/Fas has multiple tumorigenic activities. In different genetically engineered mouse models tumor-expressed CD95 was shown to be critical for cell growth.
Abdul S. Qadir   +18 more
doaj   +1 more source

Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation

open access: yesiScience, 2022
Summary: The Mammary gland undergoes complicated epithelial remodeling to form lobuloalveoli during pregnancy, in which basal epithelial cells remarkably increase to form a basket-like architecture. However, it remains largely unknown how dormant mammary
Ruiqi Liu   +11 more
doaj   +1 more source

BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions

open access: yesStem Cell Reports, 2014
B-lymphocyte-induced nuclear maturation protein 1 (BLIMP1) was previously reported to define a sebaceous gland (SG) progenitor population in the epidermis.
Kai Kretzschmar   +8 more
doaj   +1 more source

Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. [PDF]

open access: yesPLoS ONE, 2012
Induced pluripotent stem (iPS) cells can be established from somatic cells. However, there is currently no established strategy to generate corneal epithelial cells from iPS cells.
Ryuhei Hayashi   +10 more
doaj   +1 more source

Methodologies to unlock the molecular expression and cellular structure of ocular lens epithelial cells

open access: yesFrontiers in Cell and Developmental Biology, 2022
The transparent ocular lens in the anterior chamber of the eye is responsible for fine focusing of light onto the retina. The lens is entirely cellular with bulk of the tissue composed of fiber cells, and the anterior hemisphere of the lens is covered by
Justin Parreno   +8 more
doaj   +1 more source

TissueMiner: A multiscale analysis toolkit to quantify how cellular processes create tissue dynamics

open access: yeseLife, 2016
Segmentation and tracking of cells in long-term time-lapse experiments has emerged as a powerful method to understand how tissue shape changes emerge from the complex choreography of constituent cells.
Raphaël Etournay   +8 more
doaj   +1 more source

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