Results 31 to 40 of about 1,790,692 (215)

Cell jamming and unjamming in development: physical aspects [PDF]

arXiv, 2023
Collective cell migration is essential for a wide range of biological processes such as: morphogenesis, wound healing, and cancer spreading. However, it is well known that migrating epithelial collectives frequently undergo jamming, stay trapped some period of time, and then start migration again.
arxiv  

TissueMiner: A multiscale analysis toolkit to quantify how cellular processes create tissue dynamics

eLife, 2016
Segmentation and tracking of cells in long-term time-lapse experiments has emerged as a powerful method to understand how tissue shape changes emerge from the complex choreography of constituent cells.
Raphaël Etournay, Matthias Merkel, Marko Popović, Holger Brandl, Natalie A Dye, Benoît Aigouy, Guillaume Salbreux, Suzanne Eaton, Frank Jülicher   +8 more
doaj   +1 more source

Research progress in the roles of airway epithelial cells in the pathogenesis of asthma

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Asthma is a common chronic respiratory disease, and as a heterogeneous disease, it is driven by a combination of immune, genetic, and environmental factors and involves multiple cells.
XU Yinglian, TIAN Jing, ZHANG Xiang, ZHAO Shunying   +3 more
doaj   +1 more source

Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]

, 2011
Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Adamson IY, Artinian V, Aubry MC, Bai JW, Baumgartner KB, Berschneider B, Brody AR, Chen PP, Chilosi M, Chilosi M, Coalson JJ, Corrin B, Dasari V, Dissanayake SK, Dobbs LG, Flozak AS, Fukuda Y, Ha HY, Haddad R, Herzog EL, Hironaka M, Hu J, Huang CL, Hubbard R, Huber MA, Jayachandran A, Kasai H, Kasper M, Kato N, Kawasaki H, Kawasaki H, Kim J, Kim K, Kim KK, Kuwano K, Königshoff M, Königshoff M, Königshoff M, Lee JM, Liu L, Maher TM, Margalit O, Mason RJ, Matthay MA, Mazieres J, Melanie Königshoff, Moon RT, Nagai A, Pan LH, Park J, Pennison M, Plataki M, Qunn L, Radisky DC, Rosas IO, Sato M, Selman M, Selman M, Soon LL, Sternlicht MD, Thannickal VJ, Thiery JP, Uematsu K, Willis BC, Willis BC, Willis BC, Zavadil J   +66 more
core   +1 more source

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]

, 2012
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna, Schmidt, Katy, Stephens, David J, Townley, Anna K   +3 more
core   +2 more sources

From cells to tissue: A continuum model of epithelial mechanics [PDF]

Phys. Rev. E 96, 022418 (2017), 2016
A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite deformation, and incorporates stress and deformation tensors, which can be compared with experimental data.
arxiv   +1 more source

Emergence of epithelial cell density waves [PDF]

Soft Matter, 2017,13, 7046-7052, 2017
Epithelial cell monolayers exhibit traveling mechanical waves. We rationalize this observation thanks to a hydrodynamic description of the monolayer as a compressible, active and polar material. We show that propagating waves of the cell density, polarity, velocity and stress fields may be due to a Hopf bifurcation occurring above threshold values of ...
arxiv   +1 more source

Subconfluent ARPE-19 Cells Display Mesenchymal Cell-State Characteristics and Behave like Fibroblasts, Rather Than Epithelial Cells, in Experimental HCMV Infection Studies

Viruses, 2023
Human cytomegalovirus (HCMV) has a broad cellular tropism and epithelial cells are important physiological targets during infection. The retinal pigment epithelial cell line ARPE-19 has been used to model HCMV infection in epithelial cells for decades ...
Preethi Golconda, Mariana Andrade-Medina, Adam Oberstein   +2 more
doaj   +1 more source

The effects of growth factors on multicellular spheroids formed by chick embryonic retinal cells [PDF]

, 1997
Retinal cells from chick embryos aged 7.5 days of gestation were cultured for two months in a non-adherent suspension culture dish to study the effects of growth factors and co-culture with retinal pigment epithelial cells on their differentiation ...
Matsuo, Nobuhiko, Matsuo, Toshihiko, Takabatake, Mayumi   +2 more
core   +1 more source

Density fluctuations and border forces direct leader cell plasticity during collective epithelial migrations [PDF]

arXiv, 2021
Epithelial cell monolayers expand on substrates by forming finger-like protrusions, created by leader cells, in the monolayer boundary. Information transmission and communication between individual entities in the cohesive collective lead to long-range order, vortical structures, and disorder to ordered phase transitions. We ask the following questions:
arxiv