Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells. [PDF]
, 2012 C. albicans is one of the most common fungal pathogen of humans, causing local and superficial mucosal infections in immunocompromised individuals. Given that the key structure mediating host-C.
Tilo Biedermann (116048) +52 more
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Characterization of the spatio-temporal dynamics in thymic epithelial development [PDF]
, 2015 The work presented in this thesis is centered on the development and maturation of the epithelial compartment in the murine thymus and consequently its functional capacity to promote normal thymopoiesis. Two main aspects have been investigated in depth:
Mayer, Carlos E.
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Vesicular traffic in polarized epithelial cells : identification and characterization of general and epithelial specific factors [PDF]
, 1994 Polarized epithelial cells are differentiated into apical and basolateral plasma membrane domains separated by tight junctions. The apical cell surface usually faces the external milieu, the basolateral domain provides cell-cell and cell-substratum ...
Fiedler, Klaus
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Lung Cancer in Pulmonary Fibrosis: Tales of Epithelial Cell Plasticity [PDF]
, 2011 Lung epithelial cells exhibit a high degree of plasticity. Alterations to lung epithelial cell function are critically involved in several chronic lung diseases such as pulmonary fibrosis.
Königshoff, M. +2 more
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Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction. [PDF]
PLoS Pathogens, 2017 Oropharyngeal mucosal epithelia of fetuses/neonates/infants and the genital epithelia of adults play a critical role in HIV-1 mother-to-child transmission and sexual transmission of virus, respectively.
Aizezi Yasen +4 more
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Function of Gata-2 in thymic epithelial cells : a transcription factor identified from gene expression analysis of endodermal cells committed to thymic epithelial cell fate [PDF]
, 2010 The thymus structure composes of clear morphological regions. The T-cell precursors enter the thymus in the cortico-medullary junction and migrate through the cortex towards the sub capsular region and back through to the cortex into the medulla.
Na, Kyung-Jae
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Gonococcal invasion into epithelial cells depends on both cell polarity and ezrin.
PLoS Pathogens, 2021 Neisseria gonorrhoeae (GC) establishes infection in women from the cervix, lined with heterogeneous epithelial cells from non-polarized stratified at the ectocervix to polarized columnar at the endocervix.
Qian Yu +4 more
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A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells
EMBO Molecular Medicine, 2019 Therapeutic resistance is a major clinical challenge in oncology. Evidence identifies cancer stem cells (CSCs) as a driver of tumor evolution. Accordingly, the key stemness property unique to CSCs may represent a reservoir of therapeutic target to ...
Abir Arfaoui +20 more
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Gastroenterology Research and Practice, 2021 Objective. To investigate the histomorphological characteristics and pathological types of hyperproliferation of gastric surface epithelial cells. Methods.
Yangkun Wang +7 more
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A Benchmark for Epithelial Cell Tracking [PDF]
, 2019 Segmentation and tracking of epithelial cells in light microscopy (LM) movies of developing tissue is an abundant task in cell- and developmental biology. Epithelial cells are densely packed cells that form a honeycomb-like grid. This dense packing distinguishes membrane-stained epithelial cells from the types of objects recent cell tracking benchmarks
Jan Funke +4 more
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