Results 31 to 40 of about 56,527 (245)

Artificial intelligence facilitates clinical management of epithelial dysplasia in multiple organs [PDF]

Exploration of Digital Health Technologies
Epithelial dysplasia is a condition characterized by a spectrum of architectural and cytological alterations to the epithelium, resulting from the accumulation of genetic alterations.
Xin-Jia Cai
doaj   +1 more source

Deep learning approach to detect high-risk oral epithelial dysplasia: A step towards computer-assisted dysplasia grading

Advances in Human Biology, 2023
Introduction: Oral epithelial dysplasia (OED) is associated with high interobserver and intraobserver disagreement. With the exponential increase in the applicability of artificial intelligence tools such as deep learning (DL) in pathology, it would now ...
C Nandini, Shaik Basha, Aarchi Agarawal, R Parikh Neelampari, Krishna P Miyapuram, R Jadeja Nileshwariba   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

The expression of Cathepsin L in oral lichen planus

Journal of Oral Biology and Craniofacial Research, 2020
Background: Malignant transformation of oral lichen planus (OLP) was reported particularly in erosive type, however, it remains inconclusive. Cathepsin L was shown to promote tumor growth and invasion in many cancers. Therefore, cathepsin L expression in
Athip Kitkhajornkiat, Sorasun Rungsiyanont, Sineepat Talungchit, Pimporn Jirawechwongsakul, Patrayu Taebunpakul   +4 more
doaj   +1 more source

Oral epithelial dysplasia and aphthous ulceration in a patient with ulcerative colitis: a case report

BMC Oral Health, 2023
Background Ulcerative colitis is a chronic inflammatory disease with apparent extraintestinal manifestations, including in the oral cavity. Oral epithelial dysplasia, an exclusive histopathological diagnosis that is used to predict malignant ...
Kai Sun, Rong-Hui Xia
doaj   +1 more source

Nucleostemin upregulation and STAT3 activation as early events in oral epithelial dysplasia progression to squamous cell carcinoma

Neoplasia: An International Journal for Oncology Research, 2021
Most low-grade oral epithelial dysplasia remains static or regress, but a significant minority of them (4–11%) advances to oral squamous cell carcinoma (OSCC) within a few years.
Madeleine Crawford, Xiaoqin Liu, Yi-Shing L Cheng, Robert YL Tsai   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Altered β-catenin expression in oral mucosal dysplasia: a comparative study

Journal of Applied Oral Science, 2015
Objective The current study aimed to investigate the β-catenin expression in oral leukoplakia (OL) with different degrees of epithelial dysplasia and normal oral mucosa.Material and Methods Formalin-fixed, paraffin-embedded tissue samples of 39 OL (mild ...
Brunno Santos de Freitas SILVA, Caroline Alves de CASTRO, Sandra Lúcia Ventorin VON ZEIDLER, Suzana Cantanhede Orsini Machado de SOUSA, Aline Carvalho BATISTA, Fernanda Paula YAMAMOTO-SILVA   +5 more
doaj   +1 more source

Immuno-Histochemical and Quantitative Study of Melanocytes and Melanin Granules in Oral Epithelial Dysplasia [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Oral Epithelial dysplasia (OED) is a potentially malignant disorder that is characterized by the presence of architectural and cytological changes.
Swapna Honwad, SV Ravi, Mandana Donoghue, Manjiri Joshi   +3 more
doaj   +1 more source