Results 261 to 270 of about 212,176 (344)

Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation

open access: yesAdvanced Science, EarlyView.
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun   +8 more
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

open access: yesAdvanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao   +13 more
wiley   +1 more source

Association of cystic fibrosis transmembrane conductance regulator with epithelial sodium channel subunits carrying Liddle's syndrome mutations.

open access: yesAm J Physiol Lung Cell Mol Physiol, 2021
Rooj AK   +12 more
europepmc   +1 more source

Resolvin D1 Stimulates Alveolar Fluid Clearance through Alveolar Epithelial Sodium Channel, Na,K-ATPase via ALX/cAMP/PI3K Pathway in Lipopolysaccharide-Induced Acute Lung Injury

open access: yesJournal of Immunology, 2014
Qian Wang   +12 more
semanticscholar   +1 more source

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

open access: yesAdvanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang   +8 more
wiley   +1 more source

A novel tumor necrosis factor-mediated mechanism of direct epithelial sodium channel activation.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2014
I. Czikora   +23 more
semanticscholar   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

open access: yesAdvanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini   +24 more
wiley   +1 more source

Transient Receptor Potential Vanilloid 1 Activation by Dietary Capsaicin Promotes Urinary Sodium Excretion by Inhibiting Epithelial Sodium Channel &agr; Subunit–Mediated Sodium Reabsorption

open access: yesHYPERTENSION, 2014
Li Li   +14 more
semanticscholar   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

open access: yesAdvanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song   +11 more
wiley   +1 more source

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