Epithelial sodium channel, salt intake, and hypertension.
The epithelial sodium channel (ENaC) is a membrane protein made of three different but homologous subunits (a, b, and g) present in the apical membrane of epithelial cells of, for example, the distal nephron.
Hummler, E.
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COVID-19 and Liquid Homeostasis in the Lung-A Perspective through the Epithelial Sodium Channel (ENaC) Lens. [PDF]
Brown EF, Mitaera T, Fronius M.
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Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Quocdai Vu +4 more
wiley +1 more source
Correction to: Two adjacent phosphorylation sites in the C-terminus of the channel's α-subunit have opposing effects on epithelial sodium channel (ENaC) activity. [PDF]
Diakov A +3 more
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Background17β-estradiol can suppress acute lung injury (ALI) and regulate alveolar epithelial sodium channel (ENaC). However the relationship between these two functions remains unclear. This study is conducted to assess the role of ENaC and the PI3K/Akt/
D. Qi +6 more
semanticscholar +1 more source
Two adjacent phosphorylation sites in the C-terminus of the channel's α-subunit have opposing effects on epithelial sodium channel (ENaC) activity. [PDF]
Diakov A +3 more
europepmc +1 more source
Thiazolidinedione-Induced Fluid Retention: Recent Insights into the Molecular Mechanisms
Peroxisome proliferator-activated receptor-γ (PPARγ) agonists such as rosiglitazone and pioglitazone are used to improve insulin sensitivity in patients with diabetes mellitus.
Jerzy Bełtowski +2 more
doaj +1 more source
Cleavage of endogenous gamma ENaC and elevated abundance of alpha ENaC are associated with increased Na+ transport in response to apical fluid volume expansion in human H441 airway epithelial cells [PDF]
Chong D. Tan +5 more
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Regulation of the epithelial sodium channel (ENaC) in rat colon by MAP kinases
Der epitheliale Natriumkanal (ENaC) ist das Schlüsselprotein für die Regulation des Natriumhaushalts bei Wirbeltieren. Er befindet sich in der apikalen Membran von Epithelzellen unterschiedlicher Gewebe wie z.B.
Kunkel, Jan
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Downregulation of epithelial sodium channel (ENaC) activity in human airway epithelia after low temperature incubation. [PDF]
Yadav S +3 more
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