Results 111 to 120 of about 10,384 (209)
The R563Q Mutation of the Beta Subunit of the Epithelial Sodium Channel: Prevalence and Effect
, 2009 Hypertension is a major worldwide predictor of morbidity and mortality. The search for genes that contribute to blood pressure is ongoing. The epithelial sodium channel genes were implicated when the beta subunit (SCNN1B, gene ID 6338) was found to have ...
Jones, Dr Erika Sherad Wilshire +1 more
core
Epithelial Sodium Channel (ENaC) Trafficking and COMMD Proteins
The FASEB Journal, 2019 The epithelial sodium channel (ENaC), is assembled as a heterotrimer composed of three homologous subunits α or δ, β, and γ and is selectively permeable to Na + ions and plays an essential role in the regulation of sodium transport in the renal connecting tubule and collecting duct. Mutations
Sahib Rasulov +2 more
openaire +1 more source
Journal of Biological Chemistry, 2000 In many epithelial tissues in the body (e.g. kidney distal nephron, colon, airways) the rate of Na+ reabsorption is governed by the activity of the epithelial Na+ channel (ENaC).
O. Weisz +3 more
semanticscholar +1 more source
Heliyon, 2018 Both transient tachypnea of the newborn and neonatal respiratory distress syndrome have been associated with changes in gene expression of aquaporine-5 (AQP5) and the β subunit of the epithelial sodium channel (β-ENaC) in the respiratory epithelium ...
Fabiola Castorena-Torres +2 more
doaj +1 more source
Non‐Invasive, High‐Resolution (1H2O) Metabolic Activity Diffusion Imaging [MADI] of Rat Glioma
NMR in Biomedicine, Volume 39, Issue 3, March 2026.We employed Metabolic Activity Diffusion Imaging [MADI] and 18FDG‐PET in rats with syngeneic RG2 glioblastoma brain tumors. MADI quantifies kio (the cellular H2O efflux rate constant), cell volume (V), and cell density (ρ), without the use of contrast agents. The kioV product quantifies the rate of water efflux per cell.
Joshua W. Schlegel +9 more
wiley +1 more source
Lung organoids as a human system for Mycobacteria infection modeling and drug testing
The FEBS Journal, Volume 293, Issue 6, Page 1587-1611, March 2026.Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
Detection of Urinary Epithelial Sodium Channel (ENaC) Protein
American Journal of Clinical Medicine Research, 2018 Epithelial sodium Channel (ENaC) protein is an important substance in maintaining plasma sodium level. Its DNA sequences are similar in rat model with and without salt sensitivity, but the mRNA number increase in salt sensitive rat model with high salt diet. This condition is assumed to be similar in human.
Yulia Sofiatin, Rully MA Roesli
openaire +1 more source
Regulatory mechanisms of epithelial sodium channel
, 2010 Epithelial sodium channels (ENaC) are of immense importance, controlling Na+ transport across epithelia and thus playing a critical role in all aspects of fluid clearance as well as numerous other functions.
Wang, Su
core
Epithelial sodium channel: a ligand-gated channel?
, 2004 The epithelial sodium channel (ENaC) is a key component of the transepithelial Na+ transport. In epithelia, it is responsible for the maintenance of Na+ balance (which in turn controls extracellular fluid volume and arterial blood pressure) and the ...
Chraibi, A., Horisberger, J. D.
core +1 more source
Effects of CFTR-ENaC on spinal cord edema after spinal cord injury
Open MedicineTo explore the role of cystic fibrosis transmembrane conduction regulator (CFTR)-Epithelial sodium channel (ENaC) in spinal cord edema after spinal cord injury (SCI) and the related mechanism.
Shen Guowei +7 more
doaj +1 more source