Results 1 to 10 of about 218,559 (199)

Glycobiology of the Epithelial to Mesenchymal Transition [PDF]

Biomedicines, 2021
Glycosylation consists in the covalent, enzyme mediated, attachment of sugar chains to proteins and lipids. A large proportion of membrane and secreted proteins are indeed glycoproteins, while glycolipids are fundamental component of cell membranes.
Michela Pucci, Nadia Malagolini, Fabio Dall’Olio   +2 more
doaj   +3 more sources

Epithelial-to-Mesenchymal Transition Is Not a Major Modulating Factor in the Cytotoxic Response to Natural Products in Cancer Cell Lines

Molecules, 2021
Numerous natural products exhibit antiproliferative activity against cancer cells by modulating various biological pathways. In this study, we investigated the potential use of eight natural compounds (apigenin, curcumin, epigallocatechin gallate ...
Baris Kucukkaraduman, Ekin Gokce Cicek, Muhammad Waqas Akbar, Secil Demirkol Canli, Burcak Vural, Ali Osmay Gure   +5 more
doaj   +1 more source

Induction of the epithelial-mesenchymal transition in the endometrium by chronic endometritis in infertile patients.

PLoS ONE, 2021
BackgroundThe purpose of the present study was to evaluate the relationship between chronic endometritis and the epithelial-mesenchymal transition in the endometrium of infertile patients in the implantation phase.MethodsEndometrial biopsy specimens from
Mitsuaki Ishida, Akie Takebayashi, Fuminori Kimura, Akiko Nakamura, Jun Kitazawa, Aina Morimune, Tetsuro Hanada, Koji Tsuta, Takashi Murakami   +8 more
doaj   +1 more source

An Overview of Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Canine Tumors: How Far Have We Come?

Veterinary Sciences, 2022
Historically, pre-clinical and clinical studies in human medicine have provided new insights, pushing forward the contemporary knowledge. The new results represented a motivation for investigators in specific fields of veterinary medicine, who addressed ...
Federico Armando, Federico Mazzola, Luca Ferrari, Attilio Corradi   +3 more
doaj   +1 more source

Oestrogen-induced epithelial-mesenchymal transition (EMT) in endometriosis: Aetiology of vaginal agenesis in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome

Frontiers in Physiology, 2022
Endometriosis occurs when endometrial-like tissue forms and grows outside the uterus due to oestrogen-induced epithelial-mesenchymal transition in the female reproductive tract.
Too Lih Yuan, Nadiah Sulaiman, Abdul Ghani Nur Azurah, Manira Maarof, Rabiatul Adawiyah Razali, Muhammad Dain Yazid   +5 more
doaj   +1 more source

Emerging roles of epithelial-mesenchymal transition in hematological malignancies

Journal of Biomedical Science, 2018
Background Epithelial-mesenchymal transition is an important process in embryonic development, fibrosis, and cancer metastasis. During the progression of epithelial cancer, activation of epithelial-mesenchymal transition is tightly associated with ...
San-Chi Chen, Tsai-Tsen Liao, Muh-Hwa Yang   +2 more
doaj   +1 more source

Mesenchymal Stem Cell-Like Properties in Fibroblasts

Cellular Physiology and Biochemistry, 2014
Fibroblasts are biologically dynamic and morphologically heterogeneous and are the most abundant connective tissue cells, with diverse structures depending on their location and activity.
Yuqiao Chang, He Li, Zhikun Guo
doaj   +1 more source

Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis

Particle and Fibre Toxicology, 2023
Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools.
Shaoqi Yang, Yuheng Sun, Min Long, Xinbei Zhou, Mengqin Yuan, Liliang Yang, Wei Luo, Yusi Cheng, Xinxin Zhang, Wei Jiang, Jie Chao   +10 more
doaj   +1 more source

Mesenchymal Stromal Cells Epithelial Transition Induced by Renal Tubular Cells-Derived Extracellular Vesicles. [PDF]

PLoS ONE, 2016
Mesenchymal-epithelial interactions play an important role in renal tubular morphogenesis and in maintaining the structure of the kidney. The aim of this study was to investigate whether extracellular vesicles (EVs) produced by human renal proximal ...
Giulia Chiabotto, Stefania Bruno, Federica Collino, Giovanni Camussi   +3 more
doaj   +1 more source

Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies [PDF]

Romanian Medical Journal, 2022
In the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising ...
Irina Balescu, Nicoale Bacalbasa, Iulian Brezean, Claudia Stoica, Cezar Laurentiu Tomescu, Cristina Martac, Andrei Voichitoiu, Bogdan Gaspar   +7 more
doaj   +1 more source