Results 1 to 10 of about 311,587 (357)

The Clinical Relevance of Epithelial-to-Mesenchymal Transition Hallmarks: A Cut-Off-Based Approach in Healthy and Cancerous Cell Lines. [PDF]

Int J Mol Sci
The atypical activation of the epithelial-to-mesenchymal transition represents one of the main mechanisms driving cancer cell dissemination. It enables epithelial cancer cells to detach from the primary tumor mass and gain survival advantages in the ...
Rapanotti MC, Cugini E, Scioli MG, Cenci T, Anzillotti S, Puzzuoli M, Terrinoni A, Ferlosio A, De Luca A, Orlandi A.   +9 more
europepmc   +3 more sources

Epithelial-to-Mesenchymal Transition Is Not a Major Modulating Factor in the Cytotoxic Response to Natural Products in Cancer Cell Lines

Molecules, 2021
Numerous natural products exhibit antiproliferative activity against cancer cells by modulating various biological pathways. In this study, we investigated the potential use of eight natural compounds (apigenin, curcumin, epigallocatechin gallate ...
Baris Kucukkaraduman, Ekin Gokce Cicek, Muhammad Waqas Akbar, Secil Demirkol Canli, Burcak Vural, Ali Osmay Gure   +5 more
doaj   +1 more source

An Overview of Epithelial-to-Mesenchymal Transition and Mesenchymal-to-Epithelial Transition in Canine Tumors: How Far Have We Come?

Veterinary Sciences, 2022
Historically, pre-clinical and clinical studies in human medicine have provided new insights, pushing forward the contemporary knowledge. The new results represented a motivation for investigators in specific fields of veterinary medicine, who addressed ...
Federico Armando, Federico Mazzola, Luca Ferrari, Attilio Corradi   +3 more
doaj   +1 more source

Induction of the epithelial-mesenchymal transition in the endometrium by chronic endometritis in infertile patients.

PLoS ONE, 2021
BackgroundThe purpose of the present study was to evaluate the relationship between chronic endometritis and the epithelial-mesenchymal transition in the endometrium of infertile patients in the implantation phase.MethodsEndometrial biopsy specimens from
Mitsuaki Ishida, Akie Takebayashi, Fuminori Kimura, Akiko Nakamura, Jun Kitazawa, Aina Morimune, Tetsuro Hanada, Koji Tsuta, Takashi Murakami   +8 more
doaj   +1 more source

Cigarette smoke extract induces a phenotypic shift in epithelial cells: involvement of HIF1α in mesenchymal transition [PDF]

, 2014
In COPD, matrix remodeling contributes to airflow limitation. Recent evidence suggests that next to fibroblasts, the process of epithelial-mesenchymal transition can contribute to matrix remodeling.
Bracke, Ken, de Theije, CC, Dentener, Mieke A, Eurlings, Irene MJ, Gosker, Harry R, Reynaert, Niki L, van den Beucken, Twan, Verhamme, Fien, Wouters, Emiel FM   +8 more
core   +10 more sources

Oestrogen-induced epithelial-mesenchymal transition (EMT) in endometriosis: Aetiology of vaginal agenesis in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome

Frontiers in Physiology, 2022
Endometriosis occurs when endometrial-like tissue forms and grows outside the uterus due to oestrogen-induced epithelial-mesenchymal transition in the female reproductive tract.
Too Lih Yuan, Nadiah Sulaiman, Abdul Ghani Nur Azurah, Manira Maarof, Rabiatul Adawiyah Razali, Muhammad Dain Yazid   +5 more
doaj   +1 more source

Clinical significance of epithelial-to-mesenchymal transition in laryngeal carcinoma: Its role in the different subsites [PDF]

, 2017
Background: During epithelial-to-mesenchymal transition, cancer cells lose adhesion capacity gaining migratory properties. The role of the process on prognosis has been evaluated in 50 cases of laryngeal carcinoma.
Carletti, R, Chiappetta, C, Cortesi, E, Di Gioia, C., Mezi, S, Nardini, A, Orsi, E, Piesco, G   +7 more
core   +1 more source

The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation [PDF]

, 2018
The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers.
A Busanello, AL Cattin, AM Cozzolino, C Battistelli, C Battistelli, C Battistelli, C Cicchini, C Cicchini, C Cicchini, C Padua Alves, Carla Cicchini, Cecilia Battistelli, Claudia Montaldo, DW Dodd, E Bolotin, F Garibaldi, F Parviz, Frank J. Gonzalez, Giovanna Sabarese, H Hagege, J Dekker, JA Bonzo, JL Rinn, K Kim, L Amicone, L Santangelo, Laura Santangelo, M Darsigny, MA Battle, Marco Tripodi, MC Tsai, MJ Milevskiy, N Skrypek, NL Lazarevich, R Kogo, RA Gupta, RE Hewitt, S Holwerda, S Satohisa, S Sekiya, SH Ahn, T Oshima, WD Garrison, Y Kamiyama, Y Nie, Y Qiao, Y Ren, YJ Geng, Z Chen, Z Yang, ZH Wu, ZQ Wu   +51 more
core   +1 more source

A systematic approach identifies FOXA1 as a key factor in the loss of epithelial traits during the epithelial-to-mesenchymal transition in lung cancer [PDF]

, 2013
Background: The epithelial-to-mesenchymal transition is an important mechanism in cancer metastasis. Although transcription factors including SNAIL, SLUG, and TWIST1 regulate the epithelial-to-mesenchymal transition, other unknown transcription factors ...
Fei, Teng, Liu, X Shirley, Meyer, Clifford A, Wang, Gang, Wang, Haiyun, Zhang, Fan   +5 more
core   +1 more source

Expression of Tumor Assosiated and Epithelial-mesenchymal Transition Markers in 2d and 3d Cell Cultures of Mcf-7 [PDF]

, 2016
The target effects on the expression of epithelial-mesenchymal transition regulation molecules are promising for cancer therapy, including breast cancer.
Herheliuk, T. (Tetiana), Ostapchenko, L. (Lyudmila), Perepelytsina, O. (Olena), Sydorenko, M. (Mykhailo), Yurchenko, N. (Natalia)   +4 more
core   +2 more sources