Results 131 to 140 of about 598,048 (347)

Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host

, 2016
The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a short timeframe provide insight into the underlying viral dynamics and the ...
Ada W.C. Yan, Antia, Badovinac, Barber, Beauchemin, Blattman, Bocharov, Bodewes, Boianelli, Boon, Bortnick, Braciale, Brown, Brown, Bui, Cao, Carolan, Carpenter, Chao, Christensen, Crowe, Davenport, De Boer, Dobrovolny, Epstein, Faroudi, Grayson, Grebe, Greenbaum, Hancioglu, Handel, Hou, Iwasaki, James M. McCaw, Jameson, Jane M. Heffernan, Jodie McVernon, Kaech, Kaech, Karen L. Laurie, Kees, Komadina, Kreijtz, Kris, Kylie M. Quinn, Laurie, Laurie, Lee, Lehmann-Grube, Luciani, Luckheeram, Marchuk, Martin, McElhaney, McMichael, Mehlhop-Williams, Miao, Miao, Murali-Krishna, Nicole L. La Gruta, Nowak, Pawelek, Pengxing Cao, Petrie, Quinn, Rammensee, Selin, Shin, Smith, Smith, Smith, Sridhar, Steel, Sze, Tanchot, Terajima, Tscharke, van Stipdonk, Veiga-Fernandes, Veiga-Fernandes, Wells, Wherry, Wirth, Wodarz, Wodarz, Yan, Yap, Yewdell, Yewdell, Zarnitsyna, Zehn   +90 more
core   +1 more source

The antibodies 3D12 and 4D12 recognise distinct epitopes and conformations of HLA-E

Frontiers in Immunology
The commonly used antibodies 3D12 and 4D12 recognise the human leukocyte antigen E (HLA-E) protein. These antibodies bind distinct epitopes on HLA-E and differ in their ability to bind alleles of the major histocompatibility complex E (MHC-E) proteins of
Simon Brackenridge, Nessy John, Klaus Früh, Persephone Borrow, Andrew J. McMichael   +4 more
doaj   +1 more source

Enterovirus A71 Proteins: Structure and Function

Frontiers in Microbiology, 2018
Enterovirus A71 (EV-A71) infection has grown to become a serious threat to global public health. It is one of the major causes of hand, foot, and mouth disease (HFMD) in infants and young children.
Jingjing Yuan, Jingjing Yuan, Li Shen, Jing Wu, Xinran Zou, Jiaqi Gu, Jianguo Chen, Lingxiang Mao   +7 more
doaj   +1 more source

Broad Neutralization of Human Immunodeficiency Virus Type 1 (HIV-1) Elicited from Human Rhinoviruses That Display the HIV-1 gp41 ELDKWA Epitope [PDF]

, 2009
Gail Ferstandig Arnold, Paola K. Velasco, Andrew K. Holmes, Terri Wrin, Sheila C. Geisler, Pham Phung, Yu‐Shi Tian, Dawn A. Resnick, Xuejun Ma, Thomas M. Mariano, Christos J. Petropoulos, John W. Taylor, Hermann Katinger, Eddy Arnold   +13 more
openalex   +1 more source

An Immunoinformatics Prediction of Novel Multi-Epitope Vaccines Candidate Against Surface Antigens of Nipah Virus [PDF]

, 2022
Md. Mahfuzur Rahman, Joynob Akter Puspo, Ahmed Ahsan Adib, Mohammad Enayet Hossain, Mohammad Mamun Alam, Sharmin Sultana, Ariful Islam, John D. Klena, Joel M. Montgomery, Syed Moinuddin Satter, Tahmina Shirin, Mohammed Ziaur Rahman   +11 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating of immunogenic hinge epitopes. [PDF]

, 2020
Toshiyuki Ota, Shunichiro Ota, Ayumi Uchino, Shuji Nagano   +3 more
openalex   +1 more source

Immunoinformatics and epitope prediction in the age of genomic medicine

Genome Medicine, 2015
Immunoinformatics involves the application of computational methods to immunological problems. Prediction of B- and T-cell epitopes has long been the focus of immunoinformatics, given the potential translational implications, and many tools have been ...
Linus Backert, O. Kohlbacher
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation

eLife, 2015
Nanobodies are single-domain antibodies of camelid origin. We generated nanobodies against the vertebrate nuclear pore complex (NPC) and used them in STORM imaging to locate individual NPC proteins with
Tino Pleiner, Mark Bates, S. Trakhanov, Chung-Tien Lee, Jan Erik Schliep, H. Chug, Marc Böhning, H. Stark, H. Urlaub, D. Görlich   +9 more
semanticscholar   +1 more source