Results 111 to 120 of about 470,180 (352)

Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection

Scientific Reports, 2017
Dengue is considered as a major health issue which causes a number of deaths worldwide each year; tropical countries are majorly affected by dengue outbreaks.
Mudassar Ali, R. Pandey, N. Khatoon, A. Narula, Amit Mishra, V. Prajapati   +5 more
semanticscholar   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Epitope-driven common subunit vaccine design against H. pylori strains

, 2018
The developing potent vaccine is a pre-emptive strategy to tackle drug abuses and maladies of multidrug-resistant Helicobacter pylori strains. Ongoing vaccine studies are being conducted, however, development is in its infancy as ineffective vaccine ...
Ravina Madhulitha Nalamolu (6115376), Chiranjeevi Pasala (6115373), Aparna R. Bitla (6115379), Sudheer Kumar Katari (5877476), Umamaheswari Amineni (6161747), Chandra Sekhar Reddy Chilamakuri (7270157)   +5 more
core   +1 more source

Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in Human Immunodeficiency Virus Type 1 infection [PDF]

, 2004
Numerous studies now support that human immunodeficiency virus type 1 (HIV-1) evolution is influenced by immune selection pressure, with population studies showing an association between specific HLA alleles and mutations within defined cytotoxic T ...
O'Sullivan, K.M., Mothe, B.R., Kalife, ET, Johnston, MN, Altfeld, M., Kalife, E.T., Strick, D.A., Lee, PK, Yu, X.G., Mallal, SA, Walker, B.D., Rosenberg, ES, Mothe, BR, Allen, T.M., Cohen, D.E., Altfeld, M, Sette, A., Walker, BD, Sette, A, John, M., Johnston, M.N., Rosenberg, E.S., O'Sullivan, KM, Le Gall, S, Allen, TM, Brander, C, John, M, Goulder, P.J.R., Brander, C., Goulder, PJ, Lichterfeld, M, Freedberg, K.A., Cohen, DE, Freedberg, KA, Mallal, S.A., Lee, P.K., Yu, XG, Le Gall, S., Lichterfeld, M., Strick, DA   +39 more
core   +1 more source

Antibodies to a Conserved Influenza Head-interface Epitope Protect by an IgG Subtype Dependent Mechanism

Cell, 2019
SUMMARY Vaccines to generate durable humoral immunity against antigenically evolving pathogens such as influenza virus must elicit antibodies that recognize conserved epitopes.
A. Watanabe, K. R. McCarthy, M. Kuraoka, A. Schmidt, Yu Adachi, T. Onodera, K. Tonouchi, Timothy M. Caradonna, G. Bajic, Shengli Song, C. McGee, G. Sempowski, F. Feng, P. Urick, T. Kepler, Yoshimasa Takahashi, S. Harrison, G. Kelsoe   +17 more
semanticscholar   +1 more source

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke, Julia Wang, Haley Newman, Evelyn Kurpiewski, Anne Reilly, Susan R. Rheingold, Gerald Wertheim, Moe Takeda, Daniel J. Zheng, Kaitlin Devine   +9 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Designing a multi-epitope based vaccine to combat Kaposi Sarcoma utilizing immunoinformatics approach

Scientific Reports, 2019
Kaposi’s sarcoma-associated herpesvirus (KSHV) responsible for causing Kaposi sarcoma (KS), an opportunistic angioproliferative neoplasm is emerging rapidly. Despite this there is no permanent cure for this disease.
Varun Chauhan, Tripti Rungta, K. Goyal, Mini P. Singh   +3 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protective antigenic sites identified in respiratory syncytial virus fusion protein reveals importance of p27 domain

EMBO Molecular Medicine, 2021
Respiratory syncytial virus (RSV) vaccines primarily focused on surface fusion (F) protein are under development. Therefore, to identify RSV‐F protective epitopes, we evaluated 14 antigenic sites recognized following primary human RSV infection.
Jeehyun Lee, Youri Lee, Laura Klenow, Elizabeth M Coyle, Juanjie Tang, Supriya Ravichandran, Hana Golding, Surender Khurana   +7 more
doaj   +1 more source