Results 11 to 20 of about 300,540 (308)
Epitope-Based Specific Antibody Modification
, 2023 Modified antibodies play essential roles in various fields, such as analysis, diagnosis, and therapy, which require modified antibodies with optimal physical and biological properties.
Saki, Horie +6 more
core +1 more source
Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors
mAbs, 2020 Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan +12 more
doaj +1 more source
Future of cancer immunotherapy using plant virus-based nanoparticles
Future Science OA, 2019 Immunotherapy potentiates a patient’s immune response against some forms of cancer, including malignant tumors. In this Special Report, we have summarized the use of nanoparticles that have been designed for use in cancer immunotherapy with particular ...
Erum Shoeb, Kathleen Hefferon
doaj +1 more source
trypanosomatics/The-Chagas-Disease-Antigen-and-Epitope-Atlas: v1.0.0
, 2023 A Trypanosoma cruzi Antigen and Epitope Atlas: deep characterization of individual antibody specificities in human Chagas Disease patients across the ...
Alejandro +2 more
core +1 more source
Understanding the T cell immune response in SARS coronavirus infection
Emerging Microbes and Infections, 2012 The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%.
Hsueh-Ling Janice Oh +3 more
doaj +1 more source
Recent Progress Towards a Gonococcal Vaccine
Frontiers in Cellular and Infection Microbiology, 2022 Gonorrhea is a global health concern. Its etiological agent, Neisseria gonorrhoeae, rapidly acquires antimicrobial resistance and does not confer protective immunity as a consequence of infection.
Stavros A. Maurakis +1 more
doaj +1 more source
Computational Design of a Novel VLP-Based Vaccine for Hepatitis B Virus
Frontiers in Immunology, 2020 Hepatitis B virus (HBV) is a global virus responsible for a universal disease burden for millions of people. Various vaccination strategies have been developed using viral vector, nucleic acid, protein, peptide, and virus-like particles (VLPs) to ...
Saeed Mobini +4 more
doaj +1 more source
Identifying New Hybrid Insulin Peptides (HIPs) in Type 1 Diabetes
Frontiers in Immunology, 2021 In 2016 Delong et al. discovered a new type of neoepitope formed by the fusion of two unrelated peptide fragments. Remarkably these neoepitopes, called hybrid insulin peptides, or HIPs, are recognized by pathogenic CD4+ T cells in the NOD mouse and human
Stuart I. Mannering +5 more
doaj +1 more source
Frontiers in Immunology, 2020 Japanese encephalitis virus (JEV) exposure or vaccination could elicit cross-reactive CD8 T cell immunity against heterologous flaviviruses in humans.
Marion Tarbe +19 more
doaj +1 more source
Current Opinion in Immunology, 1996 Epitope (determinant) spreading is the development of immune responses to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory response. The past year has seen considerable advances in our understanding of the contribution of epitope spreading to the chronic pathogenesis of experimental T-cell ...
Vanderlugt, Carol J, Miller, Stephen D
openaire +2 more sources