Results 41 to 50 of about 326,590 (304)
VirulenceHLA class I presentation of pathogen-derived peptides is essential for CD8+ T-cell recognition of Toxoplasma gondii. While in vitro MHC ligands have been documented, the in vivo ligandome during infection progression remains poorly characterized.
Ruiying Liang +10 more
doaj +1 more source
Advances in the Characterization of the T-Cell Response to Human Herpesvirus-6
Frontiers in Immunology, 2018 Human herpesvirus (HHV) 6 is thought to remain clinically latent in most individuals after primary infection and to reactivate to cause disease in persons with severe immunosuppression.
Derek J. Hanson +8 more
doaj +1 more source
Thermal and Acidic Treatments of Gluten Epitopes Affect Their Recognition by HLA-DQ2 in silico
Frontiers in Nutrition, 2021 Celiac disease (CD) is a prevalent disorder with autoimmune features. Dietary exposure of wheat gluten (including gliadins and glutenins) to the small intestine activates the gluten-reactive CD4+ T cells and controls the disease development.
Jihui Gao +13 more
doaj +1 more source
Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection
Frontiers in Immunology, 2018 Zika virus (ZIKV) has recently caused explosive outbreaks in Pacific islands, South- and Central America. Like with other flaviviruses, protective immunity is strongly dependent on potently neutralizing antibodies (Abs) directed against the viral ...
Maximilian Koblischke +8 more
doaj +1 more source
Epitope-specific antibody responses in gD2 immunized guinea pigs and humans.
, 2018 Epitope-specific antibody responses in gD2 immunized guinea pigs and humans.
Harvey M. Friedman (3682018) +7 more
core +1 more source
The Advantage of Using Immunoinformatic Tools on Vaccine Design and Development for Coronavirus
Vaccines, 2022 After the outbreak of SARS-CoV-2 by the end of 2019, the vaccine development strategies became a worldwide priority. Furthermore, the appearances of novel SARS-CoV-2 variants challenge researchers to develop new pharmacological or preventive strategies ...
Jazmín García-Machorro +3 more
doaj +1 more source
Current Opinion in Immunology, 1996 Epitope (determinant) spreading is the development of immune responses to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory response. The past year has seen considerable advances in our understanding of the contribution of epitope spreading to the chronic pathogenesis of experimental T-cell ...
Vanderlugt, Carol J, Miller, Stephen D
openaire +2 more sources
Foods, 2022 Milk protein hydrolysates are common in infant formula, but some of them retain allergenicity due to incomplete hydrolysis of the epitopes for milk allergens.
Di Liu +3 more
doaj +1 more source
Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase [PDF]
, 2011 The viral RNA-dependent RNA polymerase (RdRp; L protein) of Rift Valley fever virus (RVFV; family Bunyaviridae) is a 238 kDa protein that is crucial for the life cycle of the virus, as it catalyses both transcription of viral mRNAs and replication of the
Brennan, Benjamin +5 more
core +1 more source
Epitope-tagged Edis-p and Relish co-localize in S2 cells.
, 2022 S2 cells were transfected with various combinations of pMT, pMT-Flag-Edis-p and pMT-Relish-HA constructs, as indicated on the left. Epitope-tagged proteins were visualized by staining with antibodies against Flag (green) and HA (red) epitopes.
Shiyu Xu (9662931) +11 more
core +1 more source