Results 61 to 70 of about 470,180 (352)

IEDB-AR: immune epitope database—analysis resource in 2019

Nucleic Acids Res., 2019
The Immune Epitope Database Analysis Resource (IEDB-AR, http://tools.iedb.org/) is a companion website to the IEDB that provides computational tools focused on the prediction and analysis of B and T cell epitopes.
Sandeep Kumar Dhanda, Swapnil Mahajan, S. Paul, Zhen Yan, Haeuk Kim, M. C. Jespersen, V. Jurtz, M. Andreatta, J. Greenbaum, P. Marcatili, A. Sette, M. Nielsen, Bjoern Peters   +12 more
semanticscholar   +1 more source

Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope [PDF]

, 1991
The regulatory immediate-early (IE) protein pp89 of murine cytomegalovirus induces CD8+ T lymphocytes that protect against lethal murine cytomegalovirus infection.
Ulrich, H. Koszinowski, Koszinowski, Ulrich H., Messerle, Martin, Matthias J. Reddehase, Hansjurgen Volkmer, Reddehase, Matthias J., Del Val, Margarita, Margarita Del Val, Martin Messerle, Volkmer, Hansjürgen, Hans-jurgen Schlicht, Schlicht, Hans-Jürgen   +12 more
core   +1 more source

The Advantage of Using Immunoinformatic Tools on Vaccine Design and Development for Coronavirus

Vaccines, 2022
After the outbreak of SARS-CoV-2 by the end of 2019, the vaccine development strategies became a worldwide priority. Furthermore, the appearances of novel SARS-CoV-2 variants challenge researchers to develop new pharmacological or preventive strategies ...
Jazmín García-Machorro, Gema Lizbeth Ramírez-Salinas, Marlet Martinez-Archundia, José Correa-Basurto   +3 more
doaj   +1 more source

Epitope spreading

Current Opinion in Immunology, 1996
Epitope (determinant) spreading is the development of immune responses to endogenous epitopes secondary to the release of self antigens during a chronic autoimmune or inflammatory response. The past year has seen considerable advances in our understanding of the contribution of epitope spreading to the chronic pathogenesis of experimental T-cell ...
Vanderlugt, Carol J, Miller, Stephen D
openaire   +2 more sources

Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase [PDF]

, 2011
The viral RNA-dependent RNA polymerase (RdRp; L protein) of Rift Valley fever virus (RVFV; family Bunyaviridae) is a 238 kDa protein that is crucial for the life cycle of the virus, as it catalyses both transcription of viral mRNAs and replication of the
Brennan, Benjamin, Richard M. Elliott, Li, Ping, Ping Li, Elliott, Richard M., Benjamin Brennan   +5 more
core   +1 more source

Schematic representation of the selection and validation of new putative immunogenic targets and multi-epitope-based vaccines against P. aeruginosa strain 24Pae112 using reverse vaccinology approaches and bioinformatics tools.

, 2023
All criteria and thresholds are shown in the flowchart. OMPs, outer membrane proteins; MEVs, multi-epitope vaccines.
Behnoush Khasheii (16748697), Mahdi Torkamaneh (16748694), Narjes Noori Goodarzi (13531555), Fatemeh Haririzadeh Jouriani (16748691), Farzad Badmasti (9327920), Sepideh Fereshteh (13531558)   +5 more
core   +1 more source

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools

Frontiers in Immunology, 2020
Computational vaccinology includes epitope mapping, antigen selection, and immunogen design using computational tools. Tools that facilitate the in silico prediction of immune response to biothreats, emerging infectious diseases, and cancers can ...
Anne Searls De Groot, L. Moise, Frances E Terry, A. Gutiérrez, P. Hindocha, Guilhem Richard, D. Hoft, T. Ross, A. Noe, Yoshimasa Takahashi, V. Kotraiah, S. Silk, C. Nielsen, A. Minassian, R. Ashfield, Matthew Ardito, S. Draper, W. Martin   +17 more
semanticscholar   +1 more source

A Method for Screening Proteases That Can Specifically Hydrolyze the Epitope AA83-105 of α_s1-Casein Allergen

Foods, 2022
Milk protein hydrolysates are common in infant formula, but some of them retain allergenicity due to incomplete hydrolysis of the epitopes for milk allergens.
Di Liu, Xiaozhe Lv, Yanjun Cong, Linfeng Li   +3 more
doaj   +1 more source

Review of Immunoinformatic approaches to in-silico B-cell epitope prediction [PDF]

, 2007
In this paper, the current state of in-silico, B-cell epitope prediction is discussed. Recommendations for improving some of the approaches encountered are outlined, along with the presentation of an entirely novel technique, which uses molecular ...
Rick Reitmaier
core   +1 more source

Additional file 1 of Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS-COV-2 using immunoinformatics approach

, 2022
Additional file 1. Design of a multi-epitope-based peptide vaccine against the S and N proteins of SARS -COV-2 using Immunoinformatics Approach. ( http://galaxy.seoklab.org/cgi-bin/report_REFINE.cgi?key=27ac3cd2f0bd1f0372ce673a67eac9e1 , https://npsa ...
Farnaz Kheirandish (805358), Seyedeh Zeinab Hosseini (12044459), Arian Karimi Rouzbahani (12044456)   +2 more
core   +1 more source