Results 81 to 90 of about 470,180 (352)

GII.4 Human Norovirus: Surveying the Antigenic Landscape

Viruses, 2019
Human norovirus is the leading cause of viral acute onset gastroenteritis disease burden, with 685 million infections reported annually. Vulnerable populations, such as children under the age of 5 years, the immunocompromised, and the elderly show a need
Michael L. Mallory, Lisa C. Lindesmith, Rachel L. Graham, Ralph S. Baric   +3 more
doaj   +1 more source

Non-Toxin-Based Clostridioides difficile Vaccination Approaches

Pathogens, 2023
Clostridioides difficile (CD) is a Gram-positive, anaerobic bacterium that infects mainly hospitalized and elderly people who have been treated with long-term antibiotic therapy leading to dysbiosis.
Agnieszka Razim, Sabina Górska, Andrzej Gamian   +2 more
doaj   +1 more source

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

Identification of the Binding Epitope of an Anti-Mouse CCR6 Monoclonal Antibody (C₆Mab-13) Using 1× Alanine Scanning

Antibodies, 2023
CC chemokine receptor 6 (CCR6) is one of the members of the G-protein-coupled receptor (GPCR) family that is upregulated in many immune-related cells, such as B lymphocytes, effector and memory T cells, regulatory T cells, and immature dendritic cells ...
Tomohiro Tanaka, Mayuki Tawara, Hiroyuki Suzuki, Mika K. Kaneko, Yukinari Kato   +4 more
doaj   +1 more source

Epitope Labeling of Histidine Decarboxylase in Drosophila melanogaster [PDF]

, 2006
Histidine decarboxylase (HDC) plays a critical role in the synthesis of histamine, a central nervous system neurotransmitter used by both vertebrates and invertebrates.
Payne, Stephanie A. N.
core  

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Epitope-specific T-cell cross-reactivity between OC43 and other human coronaviruses.

, 2023
A. Screening of cross-reactive T-cell responses to eluted peptides in partially HLA-matched pre-pandemic donors. T-cell lines were expanded in vitro by stimulation with the eluted OC43 peptides, and IFN-γ responses (SFU/106 cells) to OC43 (green) or SARS-
Padma P. Nanaware (10717647), Lawrence J. Stern (49046), Aniuska Becerra-Artiles (829447), Grant C. Weaver (16699376), Khaja Muneeruddin (1517452), J. Mauricio Calvo-Calle (80390), Scott A. Shaffer (153908)   +6 more
core   +1 more source

Epitope mapping for the anti-rabbit cholesteryl ester transfer protein monoclonal antibody that selectively inhibits triglyceride transfer

Journal of Lipid Research, 1999
Among the monoclonal antibodies (Mab) against rabbit plasma cholesteryl ester transfer protein (CETP), Mab 14-8F cross-reacted with human CETP and selectively inhibited triglyceride transfer but not cholesteryl ester transfer (Ko, K. W. S., T.
Kazunori Saito, Ki-ichiro Kobori, Hideyuki Hashimoto, Sachiko Ito, Mitsuhisa Manabe, Shinji Yokoyama   +5 more
doaj   +1 more source

Evaluation of Spike Protein Epitopes by Assessing the Dynamics of Humoral Immune Responses in Moderate COVID-19

Frontiers in Immunology, 2022
The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The spike protein (S) of SARS-CoV-2 is a major target for diagnosis and vaccine development because of ...
Lingyun Chen, Lingyun Chen, Pengfei Pang, Huan Qi, Keqiang Yan, Keqiang Yan, Yan Ren, Mingliang Ma, Ruyin Cao, Hua Li, Chuansheng Hu, Yang Li, Jun Xia, Jun Xia, Danyun Lai, Yuliang Dong, Hewei Jiang, Hainan Zhang, Hong Shan, Shengce Tao, Siqi Liu, Siqi Liu   +21 more
doaj   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source