Results 31 to 40 of about 470,180 (352)
Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors
mAbs, 2020 Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan +12 more
doaj +1 more source
Journal of Medical Virology, 2020 Recently, a novel coronavirus (SARS‐COV‐2) emerged which is responsible for the recent outbreak in Wuhan, China. Genetically, it is closely related to SARS‐CoV and MERS‐CoV. The situation is getting worse and worse, therefore, there is an urgent need for
M. Bhattacharya +7 more
semanticscholar +1 more source
Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients
Cell Reports, 2021 To fully decipher the immunogenicity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein, it is essential to assess which part is highly immunogenic in a systematic way.
Yang Li +27 more
semanticscholar +1 more source
Future of cancer immunotherapy using plant virus-based nanoparticles
Future Science OA, 2019 Immunotherapy potentiates a patient’s immune response against some forms of cancer, including malignant tumors. In this Special Report, we have summarized the use of nanoparticles that have been designed for use in cancer immunotherapy with particular ...
Erum Shoeb, Kathleen Hefferon
doaj +1 more source
Journal of Biomolecular Structure and Dynamics, 2020 At present, novel Coronavirus (2019-nCoV, the causative agent of COVID-19) has caused worldwide social and economic disruption. The disturbing statistics of this infection promoted us to develop an effective vaccine candidate against the COVID-19.
Maryam Enayatkhani +8 more
semanticscholar +1 more source
Frontiers in Immunology, 2021 Schistosomiasis remains a serious health issue nowadays for an estimated one billion people in 79 countries around the world. Great efforts have been made to identify good vaccine candidates during the last decades, but only three molecules reached ...
Rodrigo C O Sanches +10 more
semanticscholar +1 more source
BioTechniques, 2008 Epitope tagging is widely used in the characterization of newly discovered proteins. This review presents an overview of how the technique evolved and how it is being used today, with a focus on its use in the study of protein-protein interactions. In addition, the evolution of the technique for proteomic analyses is described.
openaire +3 more sources
BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes
Nucleic Acids Res., 2017 Antibodies have become an indispensable tool for many biotechnological and clinical applications. They bind their molecular target (antigen) by recognizing a portion of its structure (epitope) in a highly specific manner.
M. C. Jespersen +3 more
semanticscholar +1 more source
An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study
Scientific Reports, 2020 The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over the world has led to over millions of deaths, and devastated the social, financial and political entities around the world. Without an existing effective medical therapy,
Zikun Yang, P. Bogdan, Shahin Nazarian
semanticscholar +1 more source
Understanding the T cell immune response in SARS coronavirus infection
Emerging Microbes and Infections, 2012 The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%.
Hsueh-Ling Janice Oh +3 more
doaj +1 more source