Results 21 to 30 of about 326,590 (304)
B-Cell Epitope Discovery: The First Protein Flexibility-Based Algorithm – Zika Virus Conserved Epitope Demonstration [PDF]
, 2020 Antibody-antigen interaction – at antigenic local environments called B-cell epitopes – is a prominent mechanism for neutralization of infection. Effective mimicry, and display, of B-cell epitopes is key to vaccine design.
Peter J., Ortoleva +2 more
core +1 more source
Potent neutralizing monoclonal antibodies against Ebola virus isolated from vaccinated donors
mAbs, 2020 Ebola virus (EBOV) can cause severe hemorrhagic fever in humans, and no approved treatment is currently available. Although several antibodies have achieved good protection in animal models, the potential emerging isolates of ebolavirus and the unknown ...
Pengfei Fan +12 more
doaj +1 more source
Retinal S-antigen Th1 cell epitope mapping in patients with Behcet's disease [PDF]
, 2009 Background - Retinal S-antigen (S-Ag) is a most characterized autoantigen of autoimmune uveitis. The recognized immunodominant epitope of human S-Ag in patients with uveitis has not been identified. In this study, we selected certain patients with active
Yang, P.Z. +6 more
core +1 more source
BioTechniques, 2008 Epitope tagging is widely used in the characterization of newly discovered proteins. This review presents an overview of how the technique evolved and how it is being used today, with a focus on its use in the study of protein-protein interactions. In addition, the evolution of the technique for proteomic analyses is described.
openaire +3 more sources
Future of cancer immunotherapy using plant virus-based nanoparticles
Future Science OA, 2019 Immunotherapy potentiates a patient’s immune response against some forms of cancer, including malignant tumors. In this Special Report, we have summarized the use of nanoparticles that have been designed for use in cancer immunotherapy with particular ...
Erum Shoeb, Kathleen Hefferon
doaj +1 more source
, 2023 The thermodynamic interactions of three proposed multi-epitope-based vaccines against P. aeruginosa with TLR1, 2, and 4.
Behnoush Khasheii (16748697) +5 more
core +1 more source
Understanding the T cell immune response in SARS coronavirus infection
Emerging Microbes and Infections, 2012 The severe acute respiratory syndrome (SARS) epidemic started in late 2002 and swiftly spread across 5 continents with a mortality rate of around 10%.
Hsueh-Ling Janice Oh +3 more
doaj +1 more source
Recent Progress Towards a Gonococcal Vaccine
Frontiers in Cellular and Infection Microbiology, 2022 Gonorrhea is a global health concern. Its etiological agent, Neisseria gonorrhoeae, rapidly acquires antimicrobial resistance and does not confer protective immunity as a consequence of infection.
Stavros A. Maurakis +1 more
doaj +1 more source
trypanosomatics/The-Chagas-Disease-Antigen-and-Epitope-Atlas: v1.0.0
, 2023 A Trypanosoma cruzi Antigen and Epitope Atlas: deep characterization of individual antibody specificities in human Chagas Disease patients across the ...
Alejandro +2 more
core +1 more source
Computational Design of a Novel VLP-Based Vaccine for Hepatitis B Virus
Frontiers in Immunology, 2020 Hepatitis B virus (HBV) is a global virus responsible for a universal disease burden for millions of people. Various vaccination strategies have been developed using viral vector, nucleic acid, protein, peptide, and virus-like particles (VLPs) to ...
Saeed Mobini +4 more
doaj +1 more source