Results 21 to 30 of about 300,540 (308)

B-Cell Epitope Discovery: The First Protein Flexibility-Based Algorithm – Zika Virus Conserved Epitope Demonstration

open access: yes, 2020
Antibody-antigen interaction – at antigenic local environments called B-cell epitopes – is a prominent mechanism for neutralization of infection. Effective mimicry, and display, of B-cell epitopes is key to vaccine design.
Peter J., Ortoleva   +2 more
core   +1 more source

The thermodynamic interactions of three proposed multi-epitope-based vaccines against P. aeruginosa with TLR1, 2, and 4.

open access: yes, 2023
The thermodynamic interactions of three proposed multi-epitope-based vaccines against P. aeruginosa with TLR1, 2, and 4.
Behnoush Khasheii (16748697)   +5 more
core   +1 more source

Analisis Epitope Sel T pada SARS-Cov2 dengan Pendekatan Bioinformatika

open access: yesJurnal Nasional Teknik Elektro dan Teknologi Informasi, 2020
Pada awal tahun 2020 dunia digemparkan dengan tersebarnya wabah secara global yang menyerang pernapasan seperti wabah SARS pada tahun 2003, yaitu COVID-19. Virus penyebab wabah yang bernama SARS-Cov2 ini ternyata memiliki kemiripan ~87.5% dengan SARS-Cov.
Miftahurrahma Rosyda   +1 more
doaj   +1 more source

Functional epitopes and neutralizing antibodies of vaccinia virus

open access: yesFrontiers in Microbiology, 2023
Smallpox is an infectious disease caused by the variola virus, and it has a high mortality rate. Historically it has broken out in many countries and it was a great threat to human health.
Fenghao Peng   +12 more
doaj   +1 more source

The amino acids differences in epitopes may promote the different allergenicity of ovomucoid derived from hen eggs and quail eggs

open access: yesFood Science and Human Wellness, 2023
Quail egg ovomucoid can inhibit activation of basophils and eosinophils, while hen egg ovomucoid has been shown to be a major allergen, named Gal d 1. At present, the differences in structure and function between two ovomucoid are unclear.
Mengzhen Hao   +3 more
doaj   +1 more source

Identification and profiling of HLA-A*02:01-restricted Toxoplasma gondii peptides through immunopeptidomics in HLA-A2.1 transgenic mice

open access: yesVirulence
HLA class I presentation of pathogen-derived peptides is essential for CD8+ T-cell recognition of Toxoplasma gondii. While in vitro MHC ligands have been documented, the in vivo ligandome during infection progression remains poorly characterized.
Ruiying Liang   +10 more
doaj   +1 more source

Advances in the Characterization of the T-Cell Response to Human Herpesvirus-6

open access: yesFrontiers in Immunology, 2018
Human herpesvirus (HHV) 6 is thought to remain clinically latent in most individuals after primary infection and to reactivate to cause disease in persons with severe immunosuppression.
Derek J. Hanson   +8 more
doaj   +1 more source

Thermal and Acidic Treatments of Gluten Epitopes Affect Their Recognition by HLA-DQ2 in silico

open access: yesFrontiers in Nutrition, 2021
Celiac disease (CD) is a prevalent disorder with autoimmune features. Dietary exposure of wheat gluten (including gliadins and glutenins) to the small intestine activates the gluten-reactive CD4+ T cells and controls the disease development.
Jihui Gao   +13 more
doaj   +1 more source

Epitope-tagged Edis-p and Relish co-localize in S2 cells.

open access: yes, 2022
S2 cells were transfected with various combinations of pMT, pMT-Flag-Edis-p and pMT-Relish-HA constructs, as indicated on the left. Epitope-tagged proteins were visualized by staining with antibodies against Flag (green) and HA (red) epitopes.
Shiyu Xu (9662931)   +11 more
core   +1 more source

Structural Influence on the Dominance of Virus-Specific CD4 T Cell Epitopes in Zika Virus Infection

open access: yesFrontiers in Immunology, 2018
Zika virus (ZIKV) has recently caused explosive outbreaks in Pacific islands, South- and Central America. Like with other flaviviruses, protective immunity is strongly dependent on potently neutralizing antibodies (Abs) directed against the viral ...
Maximilian Koblischke   +8 more
doaj   +1 more source

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