Results 261 to 270 of about 607,096 (382)

Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes [PDF]

, 2005
Fariba Karamloo, Peter Schmid‐Grendelmeier, Fatimah Kussebi, Mübeccel Akdiş, Maria Salagianni, Barbara R. von Beust, Andrea Reimers, Judith Zumkehr, Л. С. Солдатова, Zora Housley-Markovic, Ulrich Müller, Thomas M. Kündig, D.M. Kemeny, Michael D. Spangfort, Kurt Blaser, Cezmi A. Akdiş   +15 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Opportunities and Challenges of mRNA and VLP Technologies for Pan-Flavivirus Vaccine Development: Focus on Conserved Quaternary Epitope Conformations. [PDF]

Int J Mol Sci
Pinzon Burgos EF, Camacho Ortega S, Atkinson B, Chua JV, Heredia A.   +4 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Highly Conserved Influenza A Nucleoprotein as a Target for Broad-Spectrum Intervention: Characterization of a Monoclonal Antibody with Pan-Influenza Reactivity. [PDF]

Vet Sci
Liu J, Gao W, Zhao K, Huang Z, Liu L, Chang J, Cao X, Zhou W, Zhou X, Liu Y, Li X, Song Y.   +11 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Taming Superbugs: Current Progress and Challenges in Combating ESKAPE Pathogens. [PDF]

Pathogens
Hetta HF, Khalaf FR, Kotb AA, Alatawi MN, Albalawi AS, Alharbi AA, Aljohani MK, Aljohani SS, Alatawi MS, Abd Ellah NH, Battah B, Donadu MG, Mazzarello V.   +12 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Mastering Immunity: Antibody Feedback as a Driver of Germinal Center Fate and Vaccine Responses. [PDF]

Eur J Immunol
Liu S, Zhang Y, Toellner KM.
europepmc   +1 more source

Phospholipase A2 Receptor 1 Epitope Spreading at Baseline Predicts Reduced Likelihood of Remission of Membranous Nephropathy.

Journal of the American Society of Nephrology, 2017
B. Seitz-Polski, H. Dębiec, A. Rousseau, K. Dahan, Christelle Zaghrini, C. Payré, V. Esnault, G. Lambeau, P. Ronco   +8 more
semanticscholar   +1 more source