Results 231 to 240 of about 98,993 (345)

Mapping of conformational epitopes of monoclonal antibodies against Escherichia coli penicillin-binding protein 1B (PBP 1B) by means of hybrid protein analysis: implications for the tertiary structure of PBP 1B

, 1990
Tanneke den Blaauwen, E Pas, A. Edelman, Brian G. Spratt, N. Nanninga   +4 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Epitope mapping of SARS-CoV-2 Spike protein using naturally-acquired immune responses to develop monoclonal antibodies. [PDF]

Sci Rep
López-Aladid R, Bueno-Freire L, Farriol-Duran R, Porta-Pardo E, Aguilar R, Vidal M, Jiménez A, Cabrera R, Vázquez N, López-Gavín A, Moncunill G, Carrascal M, García T, Lozano M, García-Basteiro AL, Dobaño C, Pazos MD, Estevez MC, Lechuga LM, Torres A, Fernández-Barat L.   +20 more
europepmc   +1 more source

Epitope Mapping by Phage Display

Japanese Journal of Thrombosis and Hemostasis, 1998
Ichiro N. Maruyama, Ichiro Kuwabara
openaire   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Epitope mapping of recombinant Salmonella enterica serotype Heidelberg flagellar hook-associated protein by in silico and in vivo approaches. [PDF]

BMC Vet Res
Yeh HY.
europepmc   +1 more source

Immunoglobulin Analysis and Epitope Mapping of F VIII Inhibitor Antibodies Developed in Two Nonhemophilic Patients Determined by Immunoblotting

, 1991
Junki Takamatsu, Kazuo Kagami, Masaki ASAI, Koji Yamamoto, Tadashi Matsushita, Isamu Sugiura, Hidehiko Saito, Yoshikatsu Sawamoto, Midori Shima, Akira Yoshioka   +9 more
openalex   +2 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Structural characterization and epitope mapping of the AAVX affinity purification ligand. [PDF]

Mol Ther Methods Clin Dev
Mietzsch M, Kamat M, Basso K, Chipman P, Huiskonen JT, McKenna R.   +5 more
europepmc   +1 more source

Epitope Mapping of the Laminin Molecule in Murine Skin Basement Membrane Zone: Demonstration of Spatial Differences in Ultrastructural Localization

, 1991
Yuji Horiguchi, Dale R. Abrahamson, Jo‐David Fine   +2 more
openalex   +2 more sources