Results 21 to 30 of about 48,164 (260)
Comparative characteristic of the methods of protein antigens epitope mapping [PDF]
The Ukrainian Biochemical Journal, 2014 Comparative analysis of experimental methods of epitope mapping of protein antigens has been carried out. The vast majority of known techniques are involved in immunochemical study of the interaction of protein molecules or peptides with antibodies of ...
O. Yu. Galkin
doaj +1 more source
eLife, 2021 Mapping polyclonal serum responses is critical to rational vaccine design. However, most high-resolution mapping approaches involve isolating and characterizing individual antibodies, which incompletely defines the polyclonal response.
Adam S Dingens +10 more
doaj +1 more source
Reverse epitope mapping of the E2 glycoprotein in antibody associated hepatitis C virus.
PLoS ONE, 2017 The humoral immune system responds to chronic hepatitis C virus (HCV) infection by producing neutralising antibodies (nAb). In this study we generated three HCV pseudoparticles in which E1E2 glycoprotein sequence was targeted by the host humoral immune ...
Amruta S Naik +8 more
doaj +1 more source
Journal of Integrative Agriculture, 2023 African swine fever virus (ASFV) is a lethal pathogen that causes severe threats to the global swine industry and it has already had catastrophic socio-economic effects. To date, no licensed prophylactic vaccine exists. Limited knowledge exists about the
Jin-xing SONG +10 more
doaj +1 more source
High-resolution epitope mapping of commercial antibodies to ANCA antigens by yeast surface display [PDF]
Journal of Immunological MethodsGabrielle Williams +2 more
exaly +2 more sources
A Linear Surface Epitope in a Proline-Rich Region of ORF3 Product of Genotype 1 Hepatitis E Virus
Viruses, 2016 Hepatitis E virus (HEV) is one of the viral pathogens causing hepatitis in humans. HEV open reading frame 3 (ORF3) encodes a small multifunctional protein (VP13), which is essential for HEV infection.
Yonglin Yang +5 more
doaj +1 more source
An overview on application of phage display technique in immunological studies
Asian Pacific Journal of Tropical Biomedicine, 2017 Phage display is very strong technique in drug discovery and development. Phage display has many applications in improving the immunological studies. Development of monoclonal antibody, peptides, peptidomimetics and epitope mapping are main application ...
Abbas Rami +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Mapping Immunodominant Antibody Epitopes of Abrin [PDF]
Antibodies, 2020 Abrin, a toxin isolated from the seeds of Abrus precatorius (jequirity pea) is considered a biological threat agent by the Center for Disease Control and Prevention. To date, there is no effective postexposure treatment for abrin poisoning, and efforts are being made to develop an efficient vaccine and measures for postexposure therapy. Epitope mapping
Ron Alcalay +6 more
openaire +3 more sources
Epitope Mapping and Tagging by Recombination PCR Mutagenesis
BioTechniques, 1997 We describe a rapid PCR method that directly inserts an epitope tag into an open reading frame (ORF) to facilitate protein detection. This project was performed within a varicella-zoster virus (VZV) system.
Christopher Hatfield +3 more
doaj +1 more source