Results 31 to 40 of about 49,871 (161)
Application of NMR Screening Methods with 19F Detection to Fluorinated Compounds Bound to Proteins
The combinational use of one-dimensional (1D) NMR-based screening techniques with 1H and 19F detections were applied to a human serum albumin–diflunisal complex.
Kazuo Furihata +2 more
doaj +1 more source
Ribosomal protein S3 (rpS3), a member of 40S small ribosomal subunit, is a multifunctional protein with various extra-ribosomal functions including DNA repair endonuclease activity and is secreted from cancer cells.
Woo-Sung Ahn +5 more
doaj +1 more source
Accurate determination of epitope for antibodies with unknown 3D structures
MAbTope is a docking-based method for the determination of epitopes. It has been used to successfully determine the epitopes of antibodies with known 3D structures.
Shifa Tahir +10 more
doaj +1 more source
A simpler and more cost-effective peptide biosynthetic method using the truncated GST as carrier for epitope mapping. [PDF]
There is a need to develop better methods for epitope mapping and/or identification of antibody-recognizing motifs. Here, we describe improved biosynthetic peptide (BSP) method using a newly developed plasmid pXXGST-3 as vector, which has a viral E7 gene
Wan-Xiang Xu +9 more
doaj +1 more source
Dengue virus (DENV) is a major public health threat worldwide. A key element in protection from dengue fever is the neutralising antibody response. Anti-dengue IgG purified from DENV-2 infected human sera showed reactivity against several peptides when ...
Babu Ramanathan +5 more
doaj +1 more source
Approximate 70% of cobra venom is composed of cytotoxin (CTX), which is responsible for the dermonecrotic symptoms of cobra envenomation. However, CTX is generally low in immunogenicity, and the antivenom is ineffective in attenuating its in vivo ...
Jia Jin Hiu +3 more
doaj +1 more source
Although computational structure prediction has had great successes in recent years, it regularly fails to predict the interactions of large protein complexes with residue-level accuracy, or even the correct orientation of the protein partners.
Minh H. Tran +9 more
doaj +1 more source
This paper describes data on allergies caused by food (vegetable) and their negative impact on the nutritional balance of the human body. Allergic responses to vegetables such as tomatoes, capsicum and spinach are next to fish, eggs and nuts.
Majeed Jamakhani +2 more
doaj +1 more source
Molecular insights into recognition of GUCY2C by T-cell engaging bispecific antibody anti-GUCY2CxCD3
The intestinal epithelial receptor Guanylyl Cyclase C (GUCY2C) is a tumor-associated cell surface antigen expressed across gastrointestinal malignancies that can serve as an efficacious target for colorectal cancer immunotherapy.
Pragya Rampuria +5 more
doaj +1 more source
Fundamentals and Methods for T- and B-Cell Epitope Prediction
Adaptive immunity is mediated by T- and B-cells, which are immune cells capable of developing pathogen-specific memory that confers immunological protection.
Jose L. Sanchez-Trincado +2 more
doaj +1 more source

