Results 51 to 60 of about 49,871 (161)

Identification of CD4+ T-cell Epitopes on Mycobacterium Tuberculosis- Secreted MPB51 Protein in C57BL/6 Mice

پزشکی بالینی ابن سینا, 2006
Introduction & Objective: Both CD4+ type 1 helper (Th1) cells and CD8+ T cells play effective roles in protection against Mycobacterium tuberculosis infection.
Ali Reza Rafiei, Yukido Kuade
doaj  

Deep learning in next-generation vaccine development for infectious diseases

Molecular Therapy: Nucleic Acids
The landscape of vaccine development was changed in the genomic era with the help of computer science. Computer-aided vaccine epitope selection has become a foundation of rational vaccine design.
Manojit Bhattacharya, Yi-Hao Lo, Srijan Chatterjee, Arpita Das, Zhi-Hong Wen, Chiranjib Chakraborty   +5 more
doaj   +1 more source

Investigation of the epitopic structure of thymosin β10 by epitope mapping experiments

Peptides, 1999
We present here a study on the epitopic structure and the immunochemical characteristics of thymosin beta10 (Tbeta10), a 43 aminoacid peptide involved in important cellular mechanisms, by using the epitope mapping Multipin method. Octapeptides overlapping by one amino acid so as to represent the whole sequence of Tbeta10 were synthesized on polystyrene
Vassiliadou, I., Leondiadis, L., Ferderigos, N., Ithakissios, D.S., Evangelatos, G.P., Livaniou, E.   +5 more
openaire   +3 more sources

Epitope Mapping of Human Alpha-Fetoprotein

Tumor Biology, 1998
Thirty monoclonal antibodies (MoAbs) to human alpha-fetoprotein (AFP) were compared with one another by two methods: Immunoaffinity electrochromatography or additive ELISA. The first method permitted to analyse the epitopes of native AFP in solution [Abelev et al., Immunol Lett 1994;40:133-138] while the other approach also detects the epitopes of ...
E F, Yakimenko, E R, Karamova, A I, Goussev, J, Hilgers, G I, Abelev, A K, Yazova   +5 more
openaire   +2 more sources

Design of Epitope-Based Vaccine Against SARS-CoV-2: An Immuno-Informatics Study

Journal of Tropical Life Science
This study aimed to develop an epitope-based vaccine of SARS-CoV-2 S protein through an immuno-informatics study. The whole genome of SARS-CoV-2 sequences was obtained from the GISAID database and then trimmed to obtain the S protein sequences.
Kavana Hafil Kusuma, Muhammad Hermawan Widyananda, Wirdatun Nafisah, Rahmat Grahadi, Yuyun Ika Christina, Dinia Rizqi Dwijayanti, Dewi Mustikaningtyas, Nashi Widodo, Muhammad Sasmito Djati   +8 more
doaj   +1 more source

Antigenic characterization and mapping of a conserved neutralizing epitope on VP1 of coxsackievirus A5

Frontiers in Immunology
BackgroundCoxsackievirus A5 (CV-A5) has re-emerged as an important pathogen associated with hand, foot, and mouth disease (HFMD) in young children. However, the antigenic structure of CV-A5 and the key determinants responsible for neutralizing antibody ...
Chen Wang, Chen Wang, Wei-Ping Jin, Jie Wu, Jie Wu, Jing Guo, Jing Guo, Sha-Sha Qian, Sha-Sha Qian, Xiao-Qi Chen, Xiao-Qi Chen, Shuo Shen, Shuo Shen   +12 more
doaj   +1 more source

epitope mapping

Citation: 'epitope mapping' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14129 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Pre-clinical allergenicity assessment of IgE epitope-targeted Der p 2 mutants demonstrate potential as hypoallergenic AIT candidates

Frontiers in Immunology
BackgroundAdvancements in hybridoma technology have enabled the production of human IgE monoclonal antibodies (hIgE mAb) for successful IgE epitope mapping of major allergens.
Glorismer Pena-Amelunxen, Mohadeseh Asghari, Kriti Khatri, Jill Glesner, Serge A. Versteeg, Serge A. Versteeg, Ronald van Ree, Ronald van Ree, Martin D. Chapman, Scott A. Smith, Maksymilian Chruszcz, Anna Pomés, Lorenz Aglas, Lorenz Aglas, Lorenz Aglas   +14 more
doaj   +1 more source

A novel approach to IgE epitope mapping - virtual epitope mapping

World Allergy Organization Journal, 2007
Fabio Dall'Antonia, Walter Keller
openaire   +1 more source

Epitope mapping and conservation of antigens from the Multi-Cruzi immunoassay platform. [PDF]

Med Microbiol Immunol
Dumonteil E, Herrera C.
europepmc   +1 more source