Results 41 to 50 of about 49,871 (161)
Virology Journal, 2019 Porcine parvovirus (PPV) is a DNA virus that causes reproductive failure in gilts and sows, resulting in embryonic and fetal losses worldwide. Epitope mapping of PPV is important for developing new vaccines. In this study, we used spot synthesis analysis
Ancelmo Rabelo de Souza +6 more
doaj +1 more source
Mapping epitope characteristics on carcinoembryonic antigen [PDF]
British Journal of Cancer, 1986 A method of epitope analysis is described in which the binding of one monoclonal antibody (MAb) to radiolabeled carcinoembryonic antigen (CEA) competes with the subsequent binding of an immobilised second MAb. From the degree of blocking obtained, we have identified both structurally related and independent epitopes on CEA.
P J, Harwood +5 more
openaire +2 more sources
Virology Journal, 2023 Background Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by the Dabie bandavirus, [or SFTS virus (SFTSV)] that has become increasingly widespread since it was first reported in 2009.
Kyungha Lee +4 more
doaj +1 more source
Epitope mapping of pathogenicLeptospiraLipL32
Letters in Applied Microbiology, 2009 To identify LipL32 epitopes and to evaluate their capability to recognize specific antibodies using ELISA.Epitope mapping by means of a library of overlapping peptide fragments prepared by simultaneous and parallel solid phase peptide synthesis on derivatized cellulose membranes (SPOT synthesis) was carried out.
Lottersberger, Javier +5 more
openaire +3 more sources
Mapping of conformational autoantibody epitopes in ZNT8 [PDF]
Diabetes/Metabolism Research and Reviews, 2011 AbstractBackgroundIdentification of the major humoral epitopes in zinc transporter 8 (ZnT8) will expand the range of biomarkers for human type 1 diabetes and may provide clues to the mechanisms governing disease progression. Our initial studies suggested that most ZnT8‐reactive sera recognize conformational epitopes in the final 100aa region of the ...
Janet M, Wenzlau +3 more
openaire +2 more sources
Characterization of antibodies directed against the Ankrd2 human muscle protein [PDF]
Archives of Biological Sciences, 2009 In order to study the function of the Ankrd2 protein, for which commercial antibodies are not available, we report the production and analysis of polyclonal antibodies to full-length Ankrd2 and its C-terminal and N-terminal regions, as well as a ...
Kojić Snežana +2 more
doaj +1 more source
MIMOX: a web tool for phage display based epitope mapping
BMC Bioinformatics, 2006 Background Phage display is widely used in basic research such as the exploration of protein-protein interaction sites and networks, and applied research such as the development of new drugs, vaccines, and diagnostics.
Honda Wataru +3 more
doaj +1 more source
Сибирский онкологический журнал, 2016 This article presents identification and mapping of an epitope in the protein ErbB-2 which binds to the monoclonal antibody 4B8 intended for use in immunochemistry to estimate the level of ErbB-2 production.
M. B. Borgoyakova, A. A. Ilichev
doaj
Human Vaccines & Immunotherapeutics, 2017 Ebola virus (EBOV) infection is highly lethal and results in severe febrile bleeding disorders that affect humans and non-human primates. One of the therapeutic approaches for treating EBOV infection focus largely on cocktails of monoclonal antibodies ...
Daniel R. Ripoll +5 more
doaj +1 more source
Structural Aspects of the Allergen-Antibody Interaction
Frontiers in Immunology, 2020 The development of allergic disease involves the production of IgE antibodies upon allergen exposure in a process called sensitization. IgE binds to receptors on the surface of mast cells and basophils, and subsequent allergen exposure leads to cross ...
Anna Pomés +2 more
doaj +1 more source