Results 161 to 170 of about 1,625,834 (280)

B-cell epitope prediction in the age of machine learning: advancements and challenges. [PDF]

J Transl Med
Gabellieri F, Singh A, Gupta S, Bensmail H, Castiglione F, Mall R.   +5 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The impact of biologically relevant negative samples on machine learning-based B-cell epitope prediction for Influenza A. [PDF]

Bioinform Adv
Pareja-Barrueto C, Reyes-Suarez J, Del Canto F, Besoain F, Angles R, Arenas-Salinas M.   +5 more
europepmc   +1 more source

Choquet Integral Algorithm for T-cell Epitope Prediction Based on Fuzzy Measure.

, 2012
[[abstract]]"Epitope is an antigen segment which is recognized by the immune system specifically and induces immune response. To accurately predict epitopes is essential in vaccine design that is one goal of immunoinformatics.
蔡政芳;Tsai, Cheng-Fang
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Genetic Variability and Conserved T-Cell Epitope Prediction of the HPV16 E1 Protein in Cervix Samples from Peru. [PDF]

Pathogens
Bonifacio-Velez de Villa E, Aguilar-Luis MA, Silva-Caso W, Becerra-Goicochea L, Tarazona-Castro Y, Aguilar-Luis D, Denegri-Hinostroza D, Cornejo-Tapia A, Aquino-Ortega R, Del Valle-Mendoza J.   +9 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

RoBep: a region-oriented deep learning model for B-cell epitope prediction. [PDF]

Bioinformatics
Xu Y, Wei G, Zhou J, Huang Y, Yu W, Lin Z, Liu R, Fan X.   +7 more
europepmc   +1 more source

Comprehensive Linear Epitope Prediction System for Host Specificity in Nodaviridae. [PDF]

Viruses, 2022
Shih TC, Ho LP, Chou HY, Wu JL, Pai TW.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source