Results 141 to 150 of about 228,208 (297)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

In vitro mutagenesis at a single residue introduces B and T cell epitopes into a class I HLA molecule. [PDF]

, 1987
Russell D. Salter, Carol Clayberger, C E Lomen, Alan M. Krensky, Peter Parham   +4 more
openalex   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Preexisting Immunity to Pandemic (H1N1) 2009

Emerging Infectious Diseases, 2009
Zheng Xing, Carol J. Cardona
doaj   +1 more source

Immunoinformatics-Based Multi-Epitope Vaccine Design Against <i>P. falciparum-</i>Causing Malaria: A Computational Approach. [PDF]

Health Sci Rep
Larbi AA, Mensah C, Korankye R, Darkwah AA, Agyemang EB, Ayikpah IY, Kwarteng A.   +6 more
europepmc   +1 more source

Identification of the sequence required for expression of the 2H4 epitope on the human leukocyte common antigens. [PDF]

, 1987
Michel Streuli, Tomohiko Matsuyama, Chikao Morimoto, Stuart F. Schlossman, Hirohisa Saito   +4 more
openalex   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Surface displayed porcine epidemic diarrhea virus membrane epitopes on <i>Lactiplantibacillus plantarum</i> stimulates antibody production in mice. [PDF]

J Anim Sci Technol
Chae JP, Vasquez R, Song JH, Pajarillo EA, Hwang IC, Kang DK.   +5 more
europepmc   +1 more source

Shigella flexneri invasion plasmid antigens B and C: epitope location and characterization with monoclonal antibodies

, 1988
J.A.N. Mills, Jerry M. Buysse, Edwin V. Oaks   +2 more
openalex   +1 more source

Laminar-specific distribution and infrastructural detail of amyloid in the Alzheimer disease cortex visualized by computer-enhanced imaging of epitopes recognized by monoclonal antibodies. [PDF]

, 1988
Ronald E. Majocha, Francine M. Beneš, Jennifer Reifel, Anne Rodenrys, Charles A. Marotta   +4 more
openalex   +1 more source