Results 191 to 200 of about 228,208 (297)

Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes. [PDF]

PLoS One
Chan QWT, Baker TC, Kuan CW, Song L, Yu H, Foster LJ.   +5 more
europepmc   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Analysis of pfhrp2 and pfhrp3 gene deletions, and the structure and variability of PfHRP2 and PfHRP3 proteins: implications for the performance of malaria rapid diagnostic tests in Cubal, Angola. [PDF]

Malar J
Mediavilla A, Molina-de la Fuente I, Martínez-Vallejo P, Francisco K, Martins JF, Febrer-Sendra B, Maturana CR, Silgado A, Nindia A, Goterris L, Martínez-Campreciós J, Oliveira-Souto I, Molina I, Berzosa P, Sulleiro E.   +14 more
europepmc   +1 more source

Identification of a F.VIII epitope recognized by a human hemophilic inhibitor [PDF]

, 1989
BC Lubahn, Jerry Ware, DW Stafford, H Reisner   +3 more
openalex   +1 more source

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Computational epitope profiling and AI-driven protein engineering enable rational design of multi-epitope vaccines against <i>Mycobacterium tuberculosis</i>. [PDF]

Comput Struct Biotechnol J
Li X, Tao X, Zhong M, Wang Y, Xue H, Andongma BT, Chou SH, Wei H, He J, Yang H.   +9 more
europepmc   +1 more source

Recognition of similar epitopes on varicella-zoster virus gpI and gpIV by monoclonal antibodies [PDF]

, 1988
Abbas Vafai, Zofia Wróblewska, Ravi Mahalingam, Gary F. Cabirac, Mary Wellish, M Cisco, Don Gilden   +6 more
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Sialic Acid-Binding Protein-1 (SABP1) of <i>Toxoplasma gondii</i>: Preliminary Computer-Based Epitope Mapping for Enhanced Vaccine Design. [PDF]

J Parasitol Res
Gholami S, Abadi AJE, Ghiabi S, Siamian D, Abdollahi H, Famili F, Yousefi A, Majidiani H.   +7 more
europepmc   +1 more source

Definition of a possible genetic basis for susceptibility to acute myelogenous leukemia associated with the presence of a polymorphic Ia epitope. [PDF]

, 1985
Stephanie Seremetis, Janet Cuttner, Robert Winchester   +2 more
openalex   +1 more source