Results 241 to 250 of about 489,867 (407)

Design of a multi-epitope vaccine against Staphylococcus Aureus lukotoxin ED using in silico approaches. [PDF]

Sci Rep
Shahraki PK, Kiani R, Siavash M, Bemani P.   +3 more
europepmc   +1 more source

Shigella flexneri invasion plasmid antigens B and C: epitope location and characterization with monoclonal antibodies [PDF]

, 1988
J.A.N. Mills, Jerry M. Buysse, Edwin V. Oaks   +2 more
openalex   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Multivalent vaccine candidate from conserved immunogenic peptides in entry or exit proteins of Orthopoxvirus genus. [PDF]

Sci Rep
de Araújo LP, Silva EN, de Alencar SM, Corsetti PP, de Almeida LA.   +4 more
europepmc   +1 more source

Epitope mapping of two major inhalant allergens, Der p I and Der f I, from mites of the genus Dermatophagoides. [PDF]

, 1987
Martin D. Chapman, Peter W. Heymann, Thomas A.E. Platts‐Mills   +2 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Development of a novel multiepitope vaccine against Menangle virus (MenV) using in-silico approaches by targeting its transmembrane proteins. [PDF]

Sci Rep
Naveed M, Ali A, Aziz T, Fatima N, Amjad S, Fatima F, Khan AA, Alharbi M, Albekairi TH, Alasmari AF.   +9 more
europepmc   +1 more source

Identification of an immunosuppressive epitope of type II collagen that confers protection against collagen-induced arthritis. [PDF]

, 1989
Linda K. Myers, J. Stuart, Jerome M. Seyer, A H Kang   +3 more
openalex   +1 more source

Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells

Nature Microbiology, 2017
Jinsheng Wen, W. Tang, Nicholas Sheets, J. Ellison, A. Sette, Kenneth Kim, S. Shresta   +6 more
semanticscholar   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source