Results 41 to 50 of about 343,320 (257)

Phage display selection of HIV specific conserved mimotopes with IgG from long-term non-progressors [PDF]

open access: yes, 2005
Poster presentation Background The aim of this study is to identify conserved epitopes of HIV-1 neutralizing antibodies in polyclonal plasma from LTNP to finally derive vaccine candidates.
Antoni, Sascha   +6 more
core   +1 more source

Prediction of T-Cell Epitope

open access: yesJournal of Pharmacological Sciences, 2007
The prevailing methods to predict T-cell epitopes are reviewed. Motif matching, matrix, support vector machine (SVM), and empirical scoring function methods are mainly reviewed; and the thermodynamic integration (TI) method using all-atom molecular dynamics (MD) simulation is mentioned briefly.
Takuya Takahashi, Hiromichi Tsurui
openaire   +5 more sources

Urinary Peptides As a Novel Source of T Cell Allergen Epitopes

open access: yesFrontiers in Immunology, 2018
Mouse allergy in both laboratory workers and in inner-city children is associated with allergic rhinitis and asthma, posing a serious public health concern.
Ricardo da Silva Antunes   +14 more
doaj   +1 more source

Large Scale Genome Analysis Shows that the Epitopes for Broadly Cross-Reactive Antibodies Are Predominant in the Pandemic 2009 Influenza Virus A H1N1 Strain

open access: yesViruses, 2013
The past pandemic strain H1N1 (A (H1N1)pdm09) has now become a common component of current seasonal influenza viruses. It has changed the pre-existing immunity of the human population to succeeding infections.
Edgar E. Lara-Ramírez   +4 more
doaj   +1 more source

Heat shock proteins may be a missing link between febrile infection and cancer tumor rejection via autoantigen molecular mimicry [PDF]

open access: yesarXiv, 2023
Numerous epidemiological studies suggest febrile infections could confer long-term immunity to certain types of cancers, though the precise mechanisms for this phenomenon remain unclear. Systemic heat-shock responses to fever may be key to understanding the overlapping outcomes of immune responses to infection and cancer. To investigate this hypothesis,
arxiv  

A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. [PDF]

open access: yes, 2018
Human botulism is most commonly caused by botulinum neurotoxin (BoNT) serotypes A, B, and E. For this work, we sought to develop a human monoclonal antibody (mAb)-based antitoxin capable of binding and neutralizing multiple subtypes of BoNT/E.
Brown, Jennifer L   +11 more
core   +2 more sources

Seeking Flavivirus Cross-Protective Immunity

open access: yesFrontiers in Immunology, 2019
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco   +4 more
doaj   +1 more source

Computational Prediction of B-cell Epitopes of Mycobacterium tuberculosis-Implications in Vaccine Design

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: Tuberculosis (TB) is a communicable disease caused by Mycobacterium tuberculosis. Bacillus Calmette-Guérin is the only vaccine available for TB.
Esakkimuthu THANGAMARIAPPAN   +2 more
doaj   +1 more source

Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies [PDF]

open access: yes, 1993
In biological fluids, hCG and its free alpha- (hCG alpha) and beta-subunits (hCG beta), occur in multiple forms. These various forms differ at the molecular level primarily in glycosylation, but also differ in protein backbone modifications corresponding
Berger, Peter   +4 more
core   +1 more source

Predicted Peptides from Non-Structural Proteins of Porcine Reproductive and Respiratory Syndrome Virus Are Able to Induce IFN-γ and IL-10

open access: yesViruses, 2013
This work describes peptides from non-structural proteins (nsp) of porcine reproductive and respiratory syndrome virus (PRRSV) predicted as potential T cell epitopes by bioinfornatics and tested for their ability to induce IFN-γ and IL-10 ...
Enric Mateu   +5 more
doaj   +1 more source

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