Results 71 to 80 of about 491,390 (408)
Viruses, 2013 The past pandemic strain H1N1 (A (H1N1)pdm09) has now become a common component of current seasonal influenza viruses. It has changed the pre-existing immunity of the human population to succeeding infections.
Edgar E. Lara-Ramírez +4 more
doaj +1 more source
Epitope Identification in BEFV Gene for Detecting Effective Points [PDF]
Journal of Advanced Biomedical Sciences, 2022 Background & Objective: The most common cause of milk production loss in cattle and water buffalo is bovine ephemeral fever (BEF). Previous cases have been reported in Iran's south regions, with a low mortality rate.
Shima Molazadeh +3 more
doaj
Uncertainty Estimation in SARS-CoV-2 B-cell Epitope Prediction for Vaccine Development [PDF]
arXiv, 2021 B-cell epitopes play a key role in stimulating B-cells, triggering the primary immune response which results in antibody production as well as the establishment of long-term immunity in the form of memory cells. Consequently, being able to accurately predict appropriate linear B-cell epitope regions would pave the way for the development of new protein-
arxiv
Innate sensing of oxidation-specific epitopes in health and disease
Nature reviews. Immunology, 2016 Ageing, infections and inflammation result in oxidative stress that can irreversibly damage cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of these deleterious consequences that not only alters lipid function but ...
C. Binder +2 more
semanticscholar +1 more source
Frontiers in GeneticsIntroductionThe immune response after transplantation depends on recipient/donor HLA allele mismatches. To enhance our understanding of the relations of HLA alleles in terms of amino-acid polymorphisms and shared epitopes, we assessed pairwise sequence ...
Ilias Doxiadis +3 more
doaj +1 more source
Seeking Flavivirus Cross-Protective Immunity
Frontiers in Immunology, 2019 The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco +4 more
doaj +1 more source
Mutation Profile of HPV16 L1 and L2 Genes in Different Geographic Areas
Viruses, 2022 The causal relationship between HPV and cervical cancer in association with the high prevalence of high risk HPV genotypes led to the design of HPV vaccines based on the major capsid L1 protein.
Dimitris Tsakogiannis +9 more
doaj +1 more source
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes
Nature Communications, 2018 The CRISPR-Cas9 system has raised hopes for developing personalized gene therapies for complex diseases. Its application for genetic and epigenetic therapies in humans raises concerns over immunogenicity of the bacterially derived Cas9 protein.
S. Ferdosi +7 more
semanticscholar +1 more source
Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis [PDF]
, 2013 PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Amor, S +13 more
core +4 more sources
Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants
VirusesCurrently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about the possibly diminished effectiveness of available
Lingyan Cui +8 more
doaj +1 more source