Results 131 to 140 of about 5,392 (239)

The N6-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma. [PDF]

Comprehensive N6-methyladenosine (m6A) epitranscriptomic profiling of primary tumors remains largely uncharted. Here, we profiled the m6A epitranscriptome of 10 nonneoplastic lung tissues and 51 lung adenocarcinoma (LUAD) tumors, integrating the ...
Ahmed, Musaddeque, Boutros, Paul, Cai, Zongwei, Chen, Moliang, Chen, Sujun, Chen, Wei, Cheng, Chao, Guan, Jiansheng, He, Housheng, Ke, Zunfu, Khan, Aafaque, Liu, Ni, Liu, Yanming, Luo, Weishan, Moran, Michael, Pham, Nhu-An, Sakashita, Shingo, Slobodyanyuk, Mykhaylo, Su, Peiran, Tsao, Ming, Wang, Lina, Wang, Shiyan, Xie, Zhongpeng, Xu, Xin, Yang, Weixiong, Yu, Jun, Zeng, Yong, Zhang, Min, Zhang, Wen, Zhang, Xinyue, Zhou, Lei, Zhu, Helen, Zhu, Lin   +32 more
core   +1 more source

The epitranscriptome and synaptic plasticity

Current Opinion in Neurobiology, 2019
RNA modifications, collectively referred to as 'the epitranscriptome,' have recently emerged as a pervasive feature of cellular mRNAs which have diverse impacts on gene expression. In the last several years, technological advances improving our ability to identify mRNA modifications, coupled with the discovery of proteins that add and remove these ...
Mathieu N Flamand, Kate D Meyer
openaire   +3 more sources

Epitranscriptomic regulations in the heart

Physiological Research
RNA modifications affect key stages of the RNA life cycle, including splicing, export, decay, and translation. Epitranscriptomic regulations therefore significantly influence cellular physiology and pathophysiology. Here, we selected some of the most abundant modifications and reviewed their roles in the heart and in cardiovascular diseases: N6 ...
Benák, D. (Daniel), Kolář, F. (František), Hlaváčková, M. (Markéta)   +2 more
openaire   +3 more sources

Doctor of Philosophy [PDF]

, 2013
dissertationPost-transcriptional RNA modifications provide new structural and functional features to modified RNA molecules. Extensive research in the past has resulted in isolation of over 100 distinct nucleotide modifications from different organisms ...
Vishteh, Vahid Khoddami
core  

High-resolution HIV-1 m6A epitranscriptome reveals isoform-dependent methylation clusters and unique 2-LTR transcript modifications

bioRxiv
The N6-methyladenosine (m6A) modification of HIV-1 has been widely studied but the number and precise positions of the m6A sites remain unclear due to the lack of precision of detection methods.
Delphine Naquin, S. Blanchet, Erwin Van Dijk, Lisa Bertrand, Sylvie Grégoire, C. Ramirez, Rania Ouazahrou, Y. Jaszczyszyn, Arnaud Moris, Claude Thermes, Celine Hernandez, O. Namy   +11 more
semanticscholar   +1 more source

From RNA and its NAD-cap: Exploring T4 phage infection from an epitranscriptomic perspective [PDF]

Bacteriophages are viruses with the ability to specifically infect and kill bacteria. Bacteriophage research has shaped our understanding of fundamental biological principles and provided tools for molecular biology, but it has long been forgotten. Thus,
Wolfram-Schauerte, Maik
core   +1 more source

Depletion of m6A-RNA in Escherichia coli reduces the infectious potential of T5 bacteriophage

Microbiology Spectrum
N6-Methyladenosine (m6A) is the most abundant internal modification of mRNA in eukaryotes that plays, among other mechanisms, an essential role in virus replication.
Bibakhya Saikia, Sebastian Riquelme-Barrios, Thomas Carell, Sophie Brameyer, Kirsten Jung   +4 more
doaj   +1 more source

Epitranscriptomics in myeloid malignancies

Blood Science, 2022
Li Han, Jianjun Chen, Rui Su
openaire   +3 more sources

Epitranscriptome regulation [PDF]

Nature Structural & Molecular Biology, 2018
Dominissini, Dan, Rechavi, Gideon
openaire   +1 more source

Editorial: Novel insights in RNA modifications: From basic to translational research

Frontiers in Cell and Developmental Biology, 2023
Huilin Huang, Chengqi Yi, Chengqi Yi, Chengqi Yi, Pengxu Qian, Pengxu Qian, Hengyou Weng, Hengyou Weng, Jianjun Chen, Jianjun Chen   +9 more
doaj   +1 more source