Results 141 to 150 of about 5,392 (239)

Abstracts

Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley   +1 more source

Studying m6A in the brain: a perspective on current methods, challenges, and future directions

Frontiers in Molecular Neuroscience
A major mechanism of post-transcriptional RNA regulation in cells is the addition of chemical modifications to RNA nucleosides, which contributes to nearly every aspect of the RNA life cycle. N6-methyladenosine (m6A) is a highly prevalent modification in
Matthew Tegowski, Kate D. Meyer, Kate D. Meyer   +2 more
doaj   +1 more source

'Oming in on RNA–protein interactions [PDF]

, 2014
Rinn, John L, Ule, Jernej
core   +1 more source

Passive shaping of intra- and intercellular m6A dynamics via mRNA metabolism

eLife
m6A is the most widespread mRNA modification and is primarily implicated in controlling mRNA stability. Fundamental questions pertaining to m6A are the extent to which it is dynamically modulated within cells and across stimuli, and the forces underlying
David Dierks, Ran Shachar, Ronit Nir, Miguel Angel Garcia-Campos, Anna Uzonyi, David Wiener, Ursula Toth, Walter Rossmanith, Lior Lasman, Boris Slobodin, Jacob H Hanna, Yaron Antebi, Ruth Scherz-Shouval, Schraga Schwartz   +13 more
doaj   +1 more source

The rRNA epitranscriptome and myonuclear SNORD landscape in skeletal muscle fibers contributes to ribosome heterogeneity and is altered by a hypertrophic stimulus

American Journal of Physiology - Cell Physiology
In cell biology, ribosomal RNA (rRNA) 2'O-methyl (2'-O-Me) is the most prevalent post-transcriptional chemical modification contributing to ribosome heterogeneity.
Minying Cui, Paulo R Jannig, Maral Halladjian, Vandré C. Figueiredo, Yuan Wen, Ivan J. Vechetti, Nicolai Krogh, Baptiste Jude, Sebastian Edman, Johanna T. Lanner, John J. McCarthy, Kevin A. Murach, T. Sejersen, Henrik Nielsen, Ferdinand von Walden   +14 more
semanticscholar   +1 more source

Epitranscriptomic modifications in plant RNAs

RNA Biology
A plethora of new and exciting findings have dramatically widened the horizons of plant RNA-related research. Despite being identified decades ago, RNA modifications were largely ignored owing to the immense difficulty in studying them with traditional ...
Susheel S. Bhat, Michel Paul, Brian D. Gregory   +2 more
doaj   +1 more source

RBM15-mediated m6A modification in cancer progression and tumor immunity: molecular mechanisms and therapeutic potential

Frontiers in Cell and Developmental Biology
RBM15, a key RNA-binding protein involved in m6A RNA methylation, plays multifaceted roles in cancer development and tumor immunity. Emerging evidence indicates that RBM15 regulates tumor cell proliferation, migration, invasion, and metabolic ...
Chunhong Li, Xiulin Jiang, Yixiao Yuan, Qiang Wang   +3 more
doaj   +1 more source

tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America
Significance Pseudomonas aeruginosa is an opportunistic pathogen, renowned for its ability to adapt to challenging conditions. In this study, we elucidated how the activity of a single gene orchestrates pathogenicity.
J. Krueger, Matthias Preusse, Nicolas Oswaldo Gomez, Y. N. Frommeyer, Sebastian Doberenz, Anne Lorenz, A. Kordes, Svenja Grobe, Mathias Müsken, D. Depledge, Sarah L. Svensson, S. Weiss, V. Kaever, Andreas Pich, Cynthia M. Sharma, Z. Ignatova, S. Häussler   +16 more
semanticscholar   +1 more source

Milk: an epigenetic amplifier of FTO-mediated transcription? Implications for Western diseases [PDF]

, 2015

core   +1 more source

The expanding role of m⁶A RNA modification in plant-virus dynamics: friend, foe, or both? [PDF]

Adv Biotechnol (Singap)
Liu JH, Yu H, Duan CG.
europepmc   +1 more source