Results 181 to 190 of about 5,392 (239)

The m⁶A-binding protein YTHDF3 modulates the cardiac response to stress. [PDF]

RNA
Rabolli CP, Das AS, Golubeva VA, van Berlo JH, Accornero F.   +4 more
europepmc   +1 more source

RNA Modifications and Their Role in Regulating KSHV Replication and Pathogenic Mechanisms. [PDF]

J Med Virol
Schultz S, Gomard-Henshaw K, Muller M.
europepmc   +1 more source

Causes and consequences of RNA:protein cross-links - lessons from chemotherapy. [PDF]

Emerg Top Life Sci
Kotopanova ZV, Wilkinson E, Zhang Z, Knight JRP.   +3 more
europepmc   +1 more source

Synonymous codon usage defines functional gene families. [PDF]

BMC Biol
Ghanegolmohammadi F, Ohnuki S, Byrne S, Raman R, Begley TJ, Dedon PC.   +5 more
europepmc   +1 more source

All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies. [PDF]

Nat Rev Mol Cell Biol
Oberdoerffer S, Gilbert WV.
europepmc   +1 more source

Unlocking the regulatory code of RNA: launching the Human RNome Project. [PDF]

Genome Biol
International Human RNome Project Consortium.
europepmc   +1 more source

Epitranscriptomic advances in normal and malignant hematopoiesis. [PDF]

Leukemia
Eleftheriou M, Russell J, Tzelepis K.
europepmc   +1 more source

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The epitranscriptome beyond m6A

Nature Reviews Genetics, 2020
Following its transcription, RNA can be modified by >170 chemically distinct types of modifications - the epitranscriptome. In recent years, there have been substantial efforts to uncover and characterize the modifications present on mRNA, motivated by the potential of such modifications to regulate mRNA fate and by discoveries and advances in our ...
David Wiener, Schraga Schwartz
semanticscholar   +3 more sources

Detecting the epitranscriptome

WIREs RNA, 2021
AbstractRNA modifications and their corresponding epitranscriptomic writer and eraser enzymes regulate gene expression. Altered RNA modification levels, dysregulated writers, and sequence changes that disrupt epitranscriptomic marks have been linked to mitochondrial and neurological diseases, cancer, and multifactorial disorders.
Anwesha Sarkar, William Gasperi, Ulrike Begley, Steven Nevins, Sabrina M. Huber, Peter C. Dedon, Thomas J. Begley   +6 more
openaire   +2 more sources

Epitranscriptomics in metabolic disease

Nature Metabolism, 2023
While epigenetic modifications of DNA and histones play main roles in gene transcription regulation, recently discovered post-transcriptional RNA modifications, known as epitranscriptomic modifications, have been found to have a profound impact on gene expression by regulating RNA stability, localization and decoding efficiency.
Yoshihiro Matsumura, Fan-Yan Wei, Juro Sakai   +2 more
openaire   +2 more sources