Eplerenone in the Treatment of Polypoidal Choroidal Vasculopathy
Case Reports in Ophthalmology, 2015 Overactivation of mineralocorticoid receptor pathways has been implicated in the pathophysiology of central serous chorioretinopathy (CSCR). Recently, mineralocorticoid receptor antagonists such as eplerenone have demonstrated success in treating ...
Kapil G. Kapoor, Alan L. Wagner
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A SELECTIVE ANTAGONIST OF MINERALOCORTICOID RECEPTOR EPLERENONE IN CARDIOLOGY PRACTICE [PDF]
Рациональная фармакотерапия в кардиологии, 2015 The role of aldosterone in pathophysiological processes is considered. The effects of the selective antagonist of mineralocorticoid receptor eplerenone are analyzed. The advantages of eplerenone compared with spironolactone are discussed.
B. B. Gegenava, O. M. Drapkina
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A Prospective Study of Eplerenone in the Treatment of Patients with Glomerulonephritis
Biomedicines, 2023 Background: High aldosterone levels contribute to kidney disease progression, while spironolactone in combination with ACEi or ARBs can potentially reduce proteinuria and ameliorate kidney function deterioration.
Marios Papasotiriou +6 more
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Effect of Eplerenone, a Selective Aldosterone Blocker, on the Development of Diabetic Nephropathy in Type 2 Diabetic Rats [PDF]
Diabetes & Metabolism Journal, 2012 BackgroundAldosterone antagonists are reported to have beneficial effects on diabetic nephropathy by effective blocking of the renin-angiotensin-aldosterone system.
Jae Hee Ahn +14 more
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Real-world practice patterns of eplerenone use for central serous chorioretinopathy [PDF]
International Journal of Retina and Vitreous, 2023 Purpose To report eplerenone use by retina specialists worldwide for central serous chorioretinopathy (CSCR). Methods A self-reporting questionnaire was distributed to retina specialists worldwide to gather clinicians’ perspectives on CSCR cases treated,
Ramesh Venkatesh +10 more
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The Journal of Clinical Hypertension, 2021 Numerous studies have demonstrated that sympathetic nervous system overactivation during exercise in hypertensive rodents and humans is due, in part, to an exaggerated reflex response known as the exercise pressor reflex.
Poghni A. Peri‐Okonny +10 more
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Safety and Antihypertensive Effect of Selara® (Eplerenone): Results from a Postmarketing Surveillance in Japan [PDF]
International Journal of Hypertension, 2016 Prospective postmarketing surveillance of Selara (eplerenone), a selective mineralocorticoid receptor antagonist, was performed to confirm its safety and efficacy for hypertension treatment in Japan.
Shoko Takahashi +6 more
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Eplerenone Attenuates Hepatic Oxidative Stress and Mitochondrial Dysfunction Following Renal Ischemia-Reperfusion Injury in Rats [PDF]
Advanced Pharmaceutical BulletinPurpose: Acute kidney injury (AKI) is frequently complicated by systemic manifestations, including hepatic dysfunction, largely due to ischemia-reperfusion (I/R) injury.
Alireza Barati +6 more
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Eplerenone for Central Serous Chorioretinopathy: Is There Still Room for This Treatment? [PDF]
BiomedicinesBackground/Objectives: The purpose of this study was to evaluate the efficacy and safety of oral eplerenone in patients with acute and chronic central serous chorioretinopathy (CSCR).
Irini Chatziralli +8 more
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Eplerenone in the treatment of central serous chorioretinopathy: a review of the literature
International Journal of Retina and Vitreous, 2018 Purpose The purpose of this review is to examine the role of eplerenone in the treatment of central serous chorioretinopathy (CSCR). Methods A comprehensive search of the PubMed database has been conducted regarding eplerenone for CSCR, while studies ...
Irini Chatziralli +6 more
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