Results 61 to 70 of about 16,960 (244)

The Pathophysiology and Treatment of Hypertension in Patients With Cushing's Syndrome [PDF]

, 2019
When hypertension, a pathology that is frequently found in the general population, presents in a young patient, secondary causes such as Cushing's syndrome (CS), a rare disease characterized by long-term elevated cortisol levels, should be considered ...
Barbot, Mattia, Ceccato, Filippo, Scaroni, Carla   +2 more
core   +1 more source

Eplerenon [PDF]

pharma-kritik, 2006
Ein mit Spironolacton verwandter Aldosteronantagonist, der sich in bestimmten Fällen von Herzinsuffizienz nach einem Infarkt vorteilhaft auswirken kann.
openaire   +1 more source

Mineralocorticoid Receptor Pathway Is a Key Mediator of Carfilzomib-induced Nephrotoxicity: Preventive Role of Eplerenone

HemaSphere, 2022
Carfilzomib is an irreversible proteasome inhibitor indicated for relapsed/refractory multiple myeloma. Carfilzomib toxicity includes renal adverse effects (RAEs) of obscure pathobiology.
P. Efentakis, S. Lamprou, M. Makridakis, I. Barla, P. Nikolaou, Andriana Christodoulou, C. Dimitriou, N. Kostomitsopoulos, I. Ntanasis‐Stathopoulos, I. Theochari, M. Gavriatopoulou, H. Gakiopoulou, A. Tasouli, A. Vlahou, E. Gikas, N. Thomaidis, M. Dimopoulos, E. Terpos, I. Andreadou   +18 more
semanticscholar   +1 more source

Oral Mineralocorticoid-Receptor Antagonists: Real-Life Experience in Clinical Subtypes of Nonresolving Central Serous Chorioretinopathy With Chronic Epitheliopathy. [PDF]

, 2016
PURPOSE: To evaluate the efficacy and safety of oral mineralocorticoid-receptor antagonist (MRa) therapy in three clinical presentations of nonresolving central serous chorioretinopathy (CSCR) with chronic epitheliopathy.
Behar-Cohen, F., Daruich, A., Dirani, A., Gallice, M., Matet, A., Nicholson, L., Sivaprasad, S.   +6 more
core   +1 more source

Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone [PDF]

, 2011
Background Inhibition of the renin-angiotensin-aldosterone system (RAAS) slows down the progression of chronic renal diseases (CKD) including IgA nephropathy (IgAN). Herein, we studied the pathogenetic roles of aldosterone (Aldo) in IgAN.
Joseph CK Leung, Loretta YY Chan, Sydney CW Tang, Man-Fai Lam, Chui-Wa Chow, Ai-Ing Lim, Kar-Neng Lai   +6 more
core   +2 more sources

Eplerenone Attenuates Fibrosis in the Contralateral Kidney of UUO Rats by Preventing Macrophage-to-Myofibroblast Transition

Frontiers in Pharmacology, 2021
Severe renal fibrosis often occurs in obstructive kidney disease, not only in the obstructed kidney but also in the contralateral kidney, causing renal dysfunction.
Yun-zhao Xiong, Yi-Ran Chang, J. Hao, Cuijuan Zhang, Fan Yang, Zhenlian Wang, Yunmeng Liu, Xiang-ting Wang, S. Mu, Qingyou Xu   +9 more
semanticscholar   +1 more source

Selection of a mineralocorticoid receptor antagonist for patients with hypertension or heart failure [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/102661/1/ejhf31 ...
Beck, Borlaug, Brilla, Burgess, Böhm, Chai, Chapman, Chatterjee, Cheng, Croom, Davies, Desai, Deswal, Edelmann, Fagart, Flack, Fletcher, Gardiner, Gasparo, Gerstein, Hernandez, Hollenberg, Iqbal, Jessup, Jeunemaitre, Joffe, Karagiannis, Kosmala, Krum, Kursaklioglu, Mak, Mansia, Maron, Martyniuk, McKelvie, McKenna, McKenna, McMurray, Michea, Parthasarathy, Pitt, Pitt, Pitt, Preiss, Ramirez-Gil, Rose, Saruta, Sato, Savoia, Sternon, Struthers, Swaminathan, Tamirisa, Tomova, Van Belle, Wakabayashi, Ward, Wei, Weinberger, White, Yamaji, Yamanaka, Yee, Zannad, Zannad, Zannad   +65 more
core   +2 more sources

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Pharmacokinetic study of eplerenone in rats after long-term coadministration with buckwheat tea

Kaohsiung Journal of Medical Sciences, 2016
The aim of this study was to investigate the effect of long-term intake of Tartary buckwheat tea on the pharmacokinetics (PK) of eplerenone in rats. A validated high-performance liquid chromatography-mass spectrometry (HPLC-MS) method was established to ...
Liang Zou, Kun Jia, Rui Li, Ping Wang, Jun-Zhi Lin, Hui-Juan Chen, Gang Zhao, Lian-Xin Peng   +7 more
doaj   +1 more source

Effect of eplerenone in percutaneous coronary intervention‐treated post‐myocardial infarction patients with left ventricular systolic dysfunction: a subanalysis of the EPHESUS trial [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107536/1/ejhf88 ...
Amano, Bacchetta, Beygui, Dickstein, Endemann, Fox, Hadoke, Hunt, Iqbal, Iqbal, Ishizawa, Jessup, Kayes-Wandover, Keeley, Keidar, Kursaklioglu, McMurray, O'Gara, Pitt, Pitt, Suzuki, Thum, Van Belle, Wakabayashi, Ward, Wijns, Wu, Zannad   +27 more
core   +2 more sources