Results 71 to 80 of about 14,325 (202)

Albuminuria as a diagnostic criterion and a therapeutic target in heart failure and other cardiovascular disease

European Journal of Heart Failure, EarlyView.
The value of uACR. CKD, chronic kidney disease; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; uACR, urine albumin‐to‐creatinine ratio. Abstract The high disease burden and bidirectional relationship of chronic kidney disease (CKD), heart failure (HF) and other cardiovascular disease (CVD) necessitate the need for early ...
Biykem Bozkurt, Patrick Rossignol, Joseph A. Vassalotti   +2 more
wiley   +1 more source

Eplerenone ethanol solvate

Acta Crystallographica Section E, 2008
Eplerenone [systematic name: 7α-(methoxycarbonyl)-3-oxo-9α,11-epoxy-17α-pregn-4-ene-21,17-carbolactone], an aldosterone receptor antagonist, crystallizes from ethanol as a monosolvate, C24H30O6·C2H6O.
Duan-Jun Xu, Jing-Jing Nie, Jian-Yong Yuan, Wei-Dong Ye, Qian Yang   +4 more
doaj   +1 more source

Hypokalemic rhabdomyolysis: a rare manifestation of primary aldosteronism [PDF]

, 2015
Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well-known manifestation of hypokalemia. Primary aldosteronism is characterized by hypertension, suppressed plasma renin activity, increased aldosterone excretion and ...
CONCISTRE, ANTONIO, FIACCO, FEDERICA, LETIZIA, Claudio, MARINELLI, CRISTIANO, MITTERHOFER, Anna Paola, PETRAMALA, LUIGI, TINTI, FRANCESCA, UMBRO, ILARIA, ZAVATTO, ASSUNTA, ZINGARETTI, VIVIANA   +9 more
core  

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes [PDF]

, 2013
Cardiac steatosis and apoptosis are key processes in diabetic cardiomyopathy, but the underlying mechanisms have not been elucidated, leading to a lack of effective therapy.
Ares-Carrasco, Sara, Barbas, Coral, Caro-Vadillo, Alicia, Egido de los Ríos, Jesús, Ferrarini, Alessia, Klett-Mingo, Mercedes, Lorenzo, Óscar, Picatoste, Belén, Ramírez, Elisa, Rupérez, Francisco Javier, Tuñón, José Luis Morales   +10 more
core   +3 more sources

Medication adherence in patients with acutely decompensated heart failure: A cross‐sectional study in the emergency department (ADHF‐ED)

European Journal of Heart Failure, EarlyView.
The ADHF‐ED trial. ADHF, acutely decompensated heart failure; CHF, chronic heart failure; ED, emergency department; EF, ejection fraction; MRA, mineralocorticoid receptor antagonist; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide. Created with the support of AI (ChatGPT).
Michael Kunz, Juel Maalouli Schaar, Katharina R. Welker, Lucas Lauder, Felix Götzinger, Ingrid Kindermann, Martin Schulz, Michael Böhm, Markus R. Meyer, Felix Mahfoud   +9 more
wiley   +1 more source

Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis

ESC Heart Failure, 2020
Aims Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage. Interventions are not established.
Carsten Tschöpe, Sophie Van Linthout, Sebastian Jäger, Robert Arndt, Tobias Trippel, Irene Müller, Ahmed Elsanhoury, Susanne Rutschow, Stefan D. Anker, Heinz‐Peter Schultheiss, Matthias Pauschinger, Frank Spillmann, Kathleen Pappritz   +12 more
doaj   +1 more source

The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]

, 2015
We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa, Anna Gluba-Brzózka, Campeau, Jacek Rysz, Li, Maciej Banach, Marta Michalska-Kasiczak, Małgorzata Misztal, McCullough, Ravassa, Wei   +10 more
core   +2 more sources

Finerenone according to insulin resistance in heart failure: Insights from the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
Insulin resistance in heart failure with mildly reduced or preserved ejection fraction: insights from FINEARTS‐HF. CI, confidence interval; CV, cardiovascular; eGDR, estimated glucose disposal rate; HF, heart failure. Aims The estimated glucose disposal rate (eGDR) is a simple, non‐invasive measure of insulin resistance. In this exploratory analysis of
John W. Ostrominski, Brian L. Claggett, Akshay S. Desai, Pardeep S. Jhund, Carolyn S.P. Lam, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Katja Rohwedder, Meike Brinker, Patrick Schloemer, John J.V. McMurray, Scott D. Solomon, Muthiah Vaduganathan   +15 more
wiley   +1 more source

Eplerenone inhibits aldosterone-induced CRP generation in rat vascular smooth muscle cells by regulating the MR-ROS-ERK1/2 signal pathway

European Journal of Inflammation, 2017
Atherosclerosis is a chronic inflammatory disease in the vessel wall. As a representative inflammatory cytokine, C-reactive protein (CRP) participates in the formation and development of atherosclerosis.
Xiaolu Zhang, Juntian Liu, Xiaoming Pang, Jingjing Zhao, Shouzhu Xu, Jing Zhao   +5 more
doaj   +1 more source

Stabilization of Early Duchenne Cardiomyopathy With Aldosterone Inhibition: Results of the Multicenter AIDMD Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Duchenne muscular dystrophy incurs nearly universal dilated cardiomyopathy by the third decade of life, preceded by myocardial damage and impaired left ventricular strain by cardiac magnetic resonance.
Subha V. Raman, Kan N. Hor, Wojciech Mazur, Andrea Cardona, Xin He, Nancy Halnon, Larry Markham, Jonathan H. Soslow, Michael D. Puchalski, Scott R. Auerbach, Uyen Truong, Suzanne Smart, Beth McCarthy, Ibrahim M. Saeed, Jeffrey M. Statland, John T. Kissel, Linda H. Cripe   +16 more
doaj   +1 more source