Results 71 to 80 of about 44,698 (310)

Stability of erythropoietin repackaging in polypropylene syringes for clinical use

Saudi Pharmaceutical Journal, 2017
Introduction: Epoetin alfa (Eprex®) is a subcutaneous, injectable formulation of short half-life recombinant human erythropoietin (rHuEPO). To current knowledge there are no published studies regarding the stability of rHuEPO once repackaging occurs (r ...
Angela Marsili, Giorgia Puorro, Chiara Pane, Anna de Rosa, Giovanni Defazio, Carlo Casali, Antonio Cittadini, Giuseppe de Michele, Brunello Ettore Florio, Alessandro Filla, Francesco Saccà   +10 more
doaj   +1 more source

Effect of Budesonide Nasal Irrigation in Patients With Chronic Rhinosinusitis With Nasal Polyps Without Prior Sinus Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana, Isabela Pontes, Caio Floriano, Renato Rios, Marlos Cortez, Marcel Miyake   +5 more
wiley   +1 more source

Practical steps to develop a transcriptomic test for blood doping

Translational Exercise Biomedicine
Blood doping remains a significant problem that threatens the integrity of sport. The current indirect method for detecting blood doping involves the longitudinal measurement of an athlete’s haematological variables and identification of suspicious ...
Sutehall Shaun, Malinsky Fernanda, Voss Sven, Chester Neil, Xu Xiao, Pitsiladis Yannis   +5 more
doaj   +1 more source

Human recombinant erythropoietin improves motor function in rats with spinal cord compression-induced cervical myelopathy.

PLoS ONE, 2019
OBJECTIVE:Erythropoietin (EPO) is a clinically available hematopoietic cytokine. EPO has shown beneficial effects in the context of spinal cord injury and other neurological conditions.
Takahiro Tanaka, Hidetoshi Murata, Ryohei Miyazaki, Tetsuya Yoshizumi, Mitsuru Sato, Makoto Ohtake, Kensuke Tateishi, Phyo Kim, Tetsuya Yamamoto   +8 more
doaj   +1 more source

Epo expression.

, 2015
A: Epo protein is significant higher in serum samples after 11 weeks for both Tg (n = 10) and Wt (n = 6) mice receiving Epo 1.25 μg/mouse compared to their Controls (n = 11 and n = 9, respectively) (#P = 0.004 and *P < 0.001, ± SD).
Trine Dalsgaard (749996), Niels Marcussen (497185), Lea Pedersen (749994), Claudia R. Cecchi (749995), Frederik Dagnæs-Hansen (165563), Lise Wogensen (110156)   +5 more
core   +1 more source

Rationale of New Grading System: Central Compartment Atopic Disease

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna, Carmen Palma‐Martínez, Serafin Sánchez‐Gómez, Isam Alobid, Daniel Martin‐Jimenez, José Miguel Villacampa‐Aubá, Christian Calvo‐Henríquez, Alfonso Del Cuvillo, Alfonso Santamaría‐Gadea, Jaime González‐García, Richard J. Harvey, John M. DelGaudio   +11 more
wiley   +1 more source

Metal–Phenolic Coatings Enable Universal Design of Spherical Nucleic Acids

Angewandte Chemie, EarlyView.
A general and straightforward strategy for constructing spherical nucleic acids (SNAs) using metal–phenolic (MP) coatings has been developed. The resulting MP‐SNAs exhibit many of the hallmark SNA properties, including enhanced cellular uptake, and serve as versatile building blocks for the programmable assembly of a diverse library of nanoparticles ...
Chaojian Chen, Taokun Luo, Ye Zhang, Xiaowei Liu, Hanwen Zhang, Chad A. Mirkin   +5 more
wiley   +2 more sources

Neuronal nitric oxide synthase required for erythropoietin modulation of heart function in mice

Frontiers in Physiology
Introduction: Erythropoietin (EPO) acts primarily in regulating red blood cell production mediated by high EPO receptor (EPOR) expression in erythroid progenitor cells.
Jeeyoung Lee, Heather M. Rogers, Danielle A. Springer, Constance T. Noguchi   +3 more
doaj   +1 more source

EPO-receptor is present in mouse C2C12 and human primary skeletal muscle cells but EPO does not influence myogenesis

, 2014
The role and regulation of the pleiotropic cytokine erythropoietin (EPO) in skeletal muscle are controversial. EPO exerts its effects by binding its specific receptor (EPO-R), which activates intracellular signaling and gene transcription in response to ...
Severine Lamon (13095072), E Zacharewicz (13495228), AN Stephens (14454126), Aaron Russell (13059132)   +3 more
core  

Nonrenal regulation of EPO synthesis

, 2009
Erythropoietin (EPO) is a circulating glycoprotein hormone whose principal function is thought to be red blood cell production. It is a classic example of a hypoxia-inducible gene, and studies of the induction of EPO synthesis by low oxygen led to the ...
Weidemann, Alexander, Alexander Weidemann, Randall S. Johnson, Johnson, Randall S.   +3 more
core   +1 more source