Results 51 to 60 of about 44,698 (310)

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Baseline Soluble Anti-erythropoietin Antibody Level Is an Independent Associated Factor for Follow-Up Erythropoietin Demand in Maintenance Dialysis Patients With End-Stage Renal Disease: A Prospective Cohort Study

Frontiers in Medicine, 2020
Aims: The aim of this study was to identify the predictive role of baseline anti-erythropoietin (anti-EPO) antibody levels in follow-up EPO demand in maintenance dialysis patients with end-stage renal disease (ESRD).Methods: Baseline routine blood ...
Ying Zhang, Shi-Zhu Bian, Kun Yang, Yiqing Wang, Sha Tang, Weili Wang, Daihong Wang, Ling Nie, Jinghong Zhao   +8 more
doaj   +1 more source

Retinoic acid regulates erythropoietin production cooperatively with hypoxia-inducible factors in human iPSC-derived erythropoietin-producing cells

Scientific Reports, 2021
Erythropoietin (EPO) is a crucial hormone for erythropoiesis and produced by adult kidneys. Insufficient EPO production in chronic kidney disease (CKD) can cause renal anemia.
Naoko Katagiri, Hirofumi Hitomi, Shin-Ichi Mae, Maki Kotaka, Li Lei, Takuya Yamamoto, Akira Nishiyama, Kenji Osafune   +7 more
doaj   +1 more source

Erythropoietin reduces fat mass in female mice lacking estrogen receptor alpha

Molecular Metabolism, 2021
Objective: Erythropoietin (EPO), the cytokine required for erythropoiesis, contributes to metabolic regulation of fat mass and glycemic control. EPO treatment in mice on high-fat diets (HFD) improved glucose tolerance and decreased body weight gain via ...
Jeeyoung Lee, Mary F. Walter, Kenneth S. Korach, Constance Tom Noguchi   +3 more
doaj   +1 more source

Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis [PDF]

Expert Opinion on Therapeutic Targets, 2015
Recombinant human erythropoietin (rhEPO) is a first-line therapeutic for the anemia of chronic kidney disease, cancer chemotherapy, AIDS (Zidovudine therapy), and lower-risk myelodysplastic syndrome. However, rhEPO frequently elevates hypertension, is costly, and may affect cancer progression.
Nicole, Rainville, Edward, Jachimowicz, Don M, Wojchowski   +2 more
openaire   +2 more sources

Unraveling MXene Oxidation Mechanisms Under Realistic Gas Environments by In Situ Gas‐Cell TEM

Advanced Functional Materials, EarlyView.
Real‐time visualization of MXene degradation reveals a fundamental oxidation mechanism under oxygen and moisture environments. Using in situ gas‐cell electron microscopy, this study demonstrates that oxygen degradation drives a thermodynamically controlled high‐temperature transformation into mixed rutile/anatase phases.
Yongfa Cheng, Kunmo Koo, Zizhen Cai, Paty Meza, Yu Wen, Byungseok Seo, Yukun Liu, Xiaobing Hu, Vinayak P. Dravid   +8 more
wiley   +1 more source

ΗΙF1α, EGR1 and SP1 co-regulate the erythropoietin receptor expression under hypoxia: an essential role in the growth of non-small cell lung cancer cells

Cell Communication and Signaling, 2019
Background Overexpression of erythropoietin (EPO) and EPO receptor (EPO-R) is associated with poor prognosis in non-small-cell lung carcinoma (NSCLC). Hypoxia, a potent EPO inducer, is a major stimulating factor in the growth of solid tumors.
Tianhong Su, Pi Liu, Xinyu Ti, Shouzhen Wu, Xiaochang Xue, Zenglu Wang, Elhardji Dioum, Qiuyang Zhang   +7 more
doaj   +1 more source

Programmable Stepwise Heteroepitaxial Growth of Colloidal Crystals With Different Phases

Advanced Materials, EarlyView.
Stepwise heteroepitaxial growth is adapted to colloidal crystal engineering with DNA, enabling face‐centered cubic (fcc) facets to grow on body‐centered cubic (bcc) crystals with 110 facets. This approach tolerates large lattice mismatches, extending heteroepitaxy beyond the limits of conventional atomic systems.
Xiaowei Liu, Yuanwei Li, Ramin Yazdaanpanah, Ye Zhang, Rachel R. Chan, Xiaobing Hu, Yiming Yang, Vinayak P. Dravid, Koray Aydin, Chad A. Mirkin   +9 more
wiley   +1 more source

Transforming growth factor-β1 decreases erythropoietin production through repressing hypoxia-inducible factor 2α in erythropoietin-producing cells

Journal of Biomedical Science, 2021
Background Renal erythropoietin (EPO)-producing (REP) cells produce EPO through hypoxia-inducible factor (HIF) 2α-activated gene transcription. Insufficient EPO production leads to anemia in patients with chronic kidney disease.
Hong-Mou Shih, Szu-Yu Pan, Chih-Jen Wu, Yu-Hsiang Chou, Chun-Yuan Chen, Fan-Chi Chang, Yi-Ting Chen, Wen-Chih Chiang, Hsing-Chen Tsai, Yung-Ming Chen, Shuei-Liong Lin   +10 more
doaj   +1 more source

Self‐Soldering, Stretchable and Self‐Healing Liquid Metal Elastomer Interconnections for Soft Electronics Platforms

Advanced Materials Technologies, EarlyView.
A self‐healing and electrically conductive liquid metal elastomer enables robust self‐soldering of surface mount devices for soft electronics. Photothermally activated conductive pathways, strong pressure‐sensitive adhesion, and stable package‐integrated contacts provide high conductivity and extreme stretchability.
Su Thiri San, Ahmed Albeltagi, Mikko Nelo, Jari Juuti, Jarkko Tolvanen, Jari Hannu   +5 more
wiley   +1 more source