Results 51 to 60 of about 101,558 (168)

Mother knows worst? Fungal infection enhances corn flavonoid of wogonin to inhibit Conogethes punctiferalis larval growth

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2254-2265, June 2025.
Schematic representation of Trichoderma asperellum infection affects the flavonoid content in corn and influences the gut microbiota and juvenile hormone pathway of Conogethes punctiferalis larvae leading to growth inhibition. Summary Pathogen infection in host plants can alter the attraction and adaptability of herbivorous insects.
Qian Li, Jiayu Li, Kaining Wu, Yue Tong, Aihuan Zhang, Yanli Du   +5 more
wiley   +1 more source

Role of epoxide hydrolases in lipid metabolism [PDF]

Biochimie, 2013
Epoxide hydrolases (EH), enzymes present in all living organisms, transform epoxide-containing lipids to 1,2-diols by the addition of a molecule of water. Many of these oxygenated lipid substrates have potent biological activities: host defense, control of development, regulation of blood pressure, inflammation, and pain. In general, the bioactivity of
openaire   +3 more sources

Re‐assessment of the risks to public health related to the genotoxicity of styrene present in plastic food contact materials

EFSA Journal, Volume 23, Issue 6, June 2025.
Abstract The EFSA Panel on Food Contact Materials (FCM) was requested by the European Commission to re‐evaluate the potential genotoxicity of styrene after oral exposure and its safety for use in plastic FCM with a specific migration limit (SML) of 40 μg/kg food.
EFSA Panel on Food Contact Materials (FCM), Claude Lambré, Riccardo Crebelli, Maria Da Silva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Claudia Bolognesi, Emma Di Consiglio, Marcel Mengelers, Zainab Al Harraq, Irene Muñoz Pilar, Sandra Rainieri, Gilles Rivière   +18 more
wiley   +1 more source

N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators.

Journal of Medicinal Chemistry, 2016
Metabolic syndrome (MetS) is a multifactorial disease cluster that consists of dyslipidemia, cardiovascular disease, type 2 diabetes mellitus, and obesity.
René Blöcher, C. Lamers, Sandra K. Wittmann, D. Merk, M. Hartmann, L. Weizel, O. Diehl, A. Brüggerhoff, Marcel Boss, A. Kaiser, T. Schader, Tamara Göbel, Manuel Grundmann, C. Angioni, J. Heering, G. Geisslinger, M. Wurglics, E. Kostenis, B. Brüne, D. Steinhilber, M. Schubert-Zsilavecz, A. Kahnt, E. Proschak   +22 more
semanticscholar   +1 more source

Regulation of cardiovascular biology by microsomal epoxide hydrolase

Toxicological Research, 2021
M. Edin, D. Zeldin
semanticscholar   +1 more source

Arabidopsis thaliana EPOXIDE HYDROLASE1 (AtEH1) is a cytosolic epoxide hydrolase involved in the synthesis of poly-hydroxylated cutin monomers.

New Phytologist, 2017
Epoxide hydrolases (EHs) are present in all living organisms. They have been extensively characterized in mammals; however, their biological functions in plants have not been demonstrated.
Emmanuelle Pineau, Lin Xu, Hugues Renault, Adrien Trolet, N. Navrot, P. Ullmann, B. Légeret, G. Verdier, F. Beisson, F. Pinot   +9 more
semanticscholar   +1 more source

The Role of Cytochrome P450 Epoxygenases, Soluble Epoxide Hydrolase, and Epoxyeicosatrienoic Acids in Metabolic Diseases.

Advances in Nutrition, 2016
Metabolic diseases are associated with an increased risk of developing cardiovascular disease. The features comprising metabolic diseases include obesity, insulin resistance, hyperglycemia, hyperlipidemia, and hypertension.
Xizhen Xu, Rui Li, Guangzhi Chen, Samantha L. Hoopes, D. Zeldin, Daowen Wang   +5 more
semanticscholar   +1 more source

Chemical Proteomics Reveals Soluble Epoxide Hydrolase as a Therapeutic Target for Ocular Neovascularization.

ACS Chemical Biology, 2017
The standard-of-care therapeutics for the treatment of ocular neovascular diseases like wet age-related macular degeneration (AMD) are biologics targeting vascular endothelial growth factor signaling.
Rania S. Sulaiman, Bomina Park, Sardar Pasha Sheik Pran Babu, Yubing Si, Rakshin Kharwadkar, S. Mitter, Bit Lee, Wei Sun, X. Qi, M. Boulton, S. Meroueh, X. Fei, Seung‐Yong Seo, T. Corson   +13 more
semanticscholar   +1 more source

Expression of human liver epoxide hydrolase in Saccharomyces pombe [PDF]

, 1988
Michael R. Jackson, Brian Burchell
openalex   +1 more source

Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice

PLoS ONE, 2017
Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid into epoxyeicosatrienoic acids (EETs), which play an important role in blood pressure regulation, protection against ischemia-reperfusion injury, angiogenesis, and inflammation.
Samantha L. Hoopes, A. Gruzdev, M. Edin, Joan P. Graves, J. Bradbury, G. Flake, F. Lih, L. Degraff, D. Zeldin   +8 more
semanticscholar   +1 more source