Results 31 to 40 of about 67,478 (222)
Journal of Lipid Research, 2014 Microsomal epoxide hydrolase (EPHX1, EC 3.3.2.9) is a highly abundant α/β-hydrolase enzyme that is known for its catalytical epoxide hydrolase activity.
Kasem Nithipatikom +4 more
doaj +1 more source
Soluble Epoxide Hydrolase and Brain Cholesterol Metabolism
Frontiers in Molecular Neuroscience, 2020 The bifunctional enzyme soluble epoxide hydrolase (sEH) is found in all regions of the brain. It has two different catalytic activities, each assigned to one of its terminal domains: the C-terminal domain presents hydrolase activity, whereas the N ...
Michelle Flores Domingues +7 more
doaj +1 more source
Physiological Reports, 2021 Oxylipins are metabolites of polyunsaturated fatty acids that mediate cardiovascular health by attenuation of inflammation, vascular tone, hemostasis, and thrombosis.
Rachel E. Walker +4 more
doaj +1 more source
Angewandte Chemie, EarlyView.1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao +8 more
wiley +2 more sources
, 2022 Supplementary Figure 2. Unilateral ureteral obstruction (UUO) increases soluble epoxide hydrolase (sEH) expression and activity.
Babu Padanilam (12174263)
core +1 more source
Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase
Journal of Lipid Research, 2011 Hepoxilins are lipid signaling molecules derived from arachidonic acid through the 12-lipoxygenase pathway. These trans-epoxy hydroxy eicosanoids play a role in a variety of physiological processes, including inflammation, neurotransmission, and ...
Annette Cronin +2 more
doaj +1 more source
Redox Regulation of Soluble Epoxide Hydrolase—Implications for Cardiovascular Health and Disease
Cells, 2022 Cell responses to changes in their redox state are significantly mediated by reversible oxido-reductive post-translational modifications of proteins, potentially altering their activities or interactions.
Rebecca Charles, Philip Eaton
doaj +1 more source
Kinetic investigation on enantioselective hydrolytic resolution of epichlorohydrin by crude epoxide hydrolase from domestic duck liver [PDF]
, 2013 Enantiopure epichlorohydrin is a valuable epoxide intermediate for preparing optically active pharmaceuticals. In this study, a novel epoxide hydrolase prepared from domestic duck liver was used as biocatalyst for producing (S) - epichlorohydrin from its
Wang, J +6 more
core +1 more source
Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation
Frontiers in Pharmacology, 2021 The soluble epoxide hydrolase (sEH) enzyme is a major regulator of bioactive lipids. The enzyme is highly expressed in liver and kidney and modulates levels of endogenous epoxy-fatty acids, which have pleiotropic biological effects including limiting ...
Karen M. Wagner +3 more
doaj +1 more source
Effects of xenobiotics on expression of human microsomal epoxide hydrolase.
, 1999 Effects of xenobiotics on expression of human microsomal epoxide ...
Sonja Miloica. Marcic (7962704)
core +3 more sources