Results 71 to 80 of about 11,968 (183)
Association between the soluble epoxide hydrolase gene and preeclampsia
Hypertension in Pregnancy, 2017 Objective: In this study the association between K55R polymorphism, methylation level of the EPHX2 promoter region, and PE was investigated in 520 individuals including 260 PE patients and 260 healthy pregnant women.
Ismail Sari +3 more
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Liver Soluble Epoxide Hydrolase Regulates Behavioral and Cellular Effects of Chronic Stress
Cell Reports, 2019 Summary: Major depression is a serious global health concern; however, the pathophysiology underlying this condition remains unclear. While numerous studies have focused on brain-specific mechanisms, few have evaluated the role of peripheral organs in ...
Xi-He Qin +11 more
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Current Issues in Molecular BiologyIn this study, we investigated the regulatory roles of the juvenile hormone epoxide hydrolase (JHEH) gene in the reproductive process of female Macrobrachium nipponense. Its total cDNA length was 1848 bp, encoding for 460 amino acids.
Jisheng Wang +7 more
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Preclinical evaluation of EPHX2 inhibition as a novel treatment for inflammatory bowel disease.
PLoS ONE, 2019 Epoxyeicosatrienoic acids (EETs) are signaling lipids produced by cytochrome P450 epoxygenation of arachidonic acid, which are metabolized by EPHX2 (epoxide hydrolase 2, alias soluble epoxide hydrolase or sEH).
William C Reisdorf +17 more
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Asian Journal of Pharmaceutical Research and DevelopmentEpoxyeicosatrienoic acids (EETs) have numerous cardiovascular benefits, including vasodilation, anti-inflammatory actions, and anti-migratory effects on vascular smooth muscle cells. However, sEH, an enzyme that breaks down EETs into diols, limits these benefits.
Pooja M. Sontakke +4 more
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Symmetry breaking by enzyme-catalyzed epoxide hydrolysis
IUCrJ, 2018 Christopher J. Schofield
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Misclassification of PfEH1 and PfEH2 as Epoxide Hydrolases [PDF]
mBio, 2017 Arand, Michael, Marowsky, Anne
openaire +4 more sources