Results 91 to 100 of about 128,828 (279)

Depth‐dependent mechanisms regulate accumulation of plant‐ and microbial‐derived residues under long‐term nitrogen addition in a semiarid grassland

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant‐ and microbial‐derived residues constitute the primary sources of soil organic carbon (SOC) in grassland ecosystems. However, their differential responses to chronic nitrogen (N) enrichment and the depth‐dependent mechanisms governing their accumulation remain ...
Xiaobo Yuan   +19 more
wiley   +1 more source

CYP52X1, representing new cytochrome P450 subfamily, displays fatty acid hydroxylase activity and contributes to virulence and growth on insect cuticular substrates in entomopathogenic fungus Beauveria bassiana [PDF]

open access: yes, 2012
Infection of insects by the entomopathogenic fungus Beauveria bassiana proceeds via attachment and penetration of the host cuticle. The outermost epicuticular layer or waxy layer of the insect represents a structure rich in lipids including abundant ...
Bernard, Grausem   +6 more
core   +2 more sources

Silencing of juvenile hormone‐related genes through RNA interference leads to molt failure and high mortality in the spongy moth

open access: yesInsect Science, EarlyView.
The feasibility of using RNA interference to control the globally important quarantine pest, the spongy moth. Targeting genes related to JHs play an important role in the growth and development of insects. First, the open reading frames (ORFs) of Ldjhamt and Ldjheh were identified and characterized, and the target genes were cloned and double‐stranded ...
Wenzhuai Ji   +3 more
wiley   +1 more source

A self-compartmentalizing hexamer serine protease from Pyrococcus Horikoshii: Substrate selection achieved through multimerization [PDF]

open access: yes, 2013
Oligopeptidases impose a size limitation on their substrates, the mechanism of which has long been in debate. Here we present the structure of a hexameric serine protease, an oligopeptidase from Pyrococcus horikoshii (PhAAP), revealing a complex, self ...
Aertgeerts   +73 more
core   +1 more source

Physiological and anatomical determinants of placental drug transfer

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis   +3 more
wiley   +1 more source

Promiscuous Substrate-Binding explains the Enzymatic stereo and Regiocontrolled Synthesis of Enantiopure Hydroxy Ketones and Diols [PDF]

open access: yes, 2009
Financial support from the Spanish Ministerio de Ciencia e Innovación (MICINN, Project CTQ2007-61126) and the Spanish Ministerio de Asuntos Exteriores y de Cooperación (Programa de Cooperación Interuniversitaria, PCI Iberoamérica MAEC-AECID, Project A ...
Bennet   +51 more
core   +2 more sources

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Regulation Roles of Juvenile Hormone Epoxide Hydrolase Gene 2 in the Female River Prawn Macrobrachium nipponense Reproductive Process

open access: yesCurrent Issues in Molecular Biology
In this study, we investigated the regulatory roles of the juvenile hormone epoxide hydrolase (JHEH) gene in the reproductive process of female Macrobrachium nipponense. Its total cDNA length was 1848 bp, encoding for 460 amino acids.
Jisheng Wang   +7 more
doaj   +1 more source

Biocatalysis. Biological systems for the production of chemicals [PDF]

open access: yes, 2017
Biocatalysis harnesses the catalytic potential of enzymes to produce building blocks and end-products for the pharmaceutical and chemical industry. Located at the interface between fermentation processes and petrol-based chemistry, biotransformation ...
Held, M.   +3 more
core  

Highlights in toxicology [PDF]

open access: yes, 2011
Every year our cooperating journal, the Archives of Toxicology, publishes and analyzes its most cited articles. In 2009/2010 the most popular articles focussed on ethanol-induced liver damage, tea polyphenols as anti-carcinogens and concepts of dose ...
Marchan, R.
core  

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