Results 101 to 110 of about 43,844 (154)

Nitrogen-mediated regulation of the biosynthesis of furanocoumarin and functional characterization of

Industrial Crops and Products
Nitrogen is a key environmental factor shaping the development and accumulation of bioactive compounds in medicinal plants. In Angelica dahurica var. formosana , furanocoumarins (FCs) are the principal active constituents, yet epoxide hydrolases (EHs ...
Yanan Liu, Yijie Jiang, Changguo Nong, Yunxin Zhang, Yinyin Chen, Dongju Feng, Renlang Liu, Hailing Xu, Linke Li, Jiaxun Pu, Wei Wu   +10 more
doaj   +1 more source

Discovery and characterization of thermophilic limonene-1,2-epoxide hydrolases from hot spring metagenomic libraries

, 2015
The epoxide hydrolases (EHs) represent an attractive option for the synthesis of chiral epoxides and 1,2-diols which are valuable building blocks for the synthesis of several pharmaceutical compounds.
Christopher Sayer, Wohlgemuth, Roland, Roland Wohlgemuth, Erica Elisa Ferrandi, Celeste Annovazzi, Gianluca Iacobone, Xu Peng, Annovazzi, Celeste, Daniela Monti, Ferrandi, Erica Elisa, Marchesi, Carlotta, Jennifer A. Littlechild, Iacobone, Gianluca, Littlechild, Jennifer A., Michail N. Isupov, Sayer, Christopher, Peng, Xu, Elizaveta Bonch‐Osmolovskaya, Carlotta Marchesi, Monti, Daniela, Isupov, Michail N., Bonch-Osmolovskaya, Elizaveta, BonchOsmolovskaya Elizaveta, Iacobone Gianluca, Littlechild Jennifer A, Marchesi Carlotta, Wohlgemuth Roland, Annovazzi Celeste, Monti Daniela, Peng Xu, Isupov Michail N, Ferrandi Erica Elisa, Sayer Christopher   +32 more
core   +1 more source

Transcriptomic profiling of Debaryomyces hansenii reveals detoxification and stress responses to benzo(a)pyrene exposure

Applied and Environmental Microbiology
The environmental accumulation of polycyclic aromatic hydrocarbons (PAHs), such as benzo(a)pyrene (BaP), poses significant threats to ecosystems and public health due to their persistent nature, mutagenic potential, and well-documented carcinogenicity ...
Francisco Padilla-Garfias, Augusto César Poot-Hernández, Minerva Araiza-Villanueva, Martha Calahorra, Norma Silvia Sánchez, Antonio Peña   +5 more
doaj   +1 more source

Computational Design of Enantiocomplementary Epoxide Hydrolases for Asymmetric Synthesis of Aliphatic and Aromatic Diols. [PDF]

Chembiochem, 2020
Arabnejad H, Bombino E, Colpa DI, Jekel PA, Trajkovic M, Wijma HJ, Janssen DB.   +6 more
europepmc   +1 more source

Efficient Epoxide Hydrolase Catalyzed Resolutions of (+)- and (-)-cis/trans-Limonene Oxides

, 2015
The synthesis of enantiomerically pure cis- and trans-limonene oxides and their corresponding diols from easily accessible raw materials has been of much interest for a long time.
Ferrandi Erica Elisa, Monti Daniela, Riva Sergio, Marchesi Carlotta, Wohlgemuth Roland, Annovazzi Celeste   +5 more
core  

Enhancement of Soluble Expression and Biochemical Characterization of Two Epoxide Hydrolases from Bacillus. [PDF]

Iran J Biotechnol, 2019
Wu LY, Xu JJ, Xu P, Yong B, Feng H.
europepmc   +1 more source

Unraveling a Case Where the NAC Approach Fails─MD and QM Modeling of Regioselective cis-Stilbene Oxide Hydrolysis by Engineered Epoxide Hydrolases. [PDF]

J Chem Inf Model
Bombino E, Arabnejad H, Liu B, Jekel PA, Sheng X, Janssen DB, Himo F, Wijma HJ.   +7 more
europepmc   +1 more source

Role of epoxy-fatty acids and epoxide hydrolases in the pathology of neuro-inflammation. [PDF]

Biochimie, 2019
Kodani SD, Morisseau C.
europepmc   +1 more source

In Vitro Metabolism of Oprozomib, an Oral Proteasome Inhibitor: Role of Epoxide Hydrolases and Cytochrome P450s. [PDF]

Drug Metab Dispos, 2017
Wang Z, Fang Y, Teague J, Wong H, Morisseau C, Hammock BD, Rock DA, Wang Z.   +7 more
europepmc   +1 more source

Expanding the Catalytic Triad in Epoxide Hydrolases and Related Enzymes. [PDF]

ACS Catal, 2015
Amrein BA, Bauer P, Duarte F, Janfalk Carlsson Å, Naworyta A, Mowbray SL, Widersten M, Kamerlin SC.   +7 more
europepmc   +1 more source