Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury [PDF]
, 2016 Aims: Myocardial ischemia can result in marked mitochondrial damage leading to cardiac dysfunction, as such identifying novel mechanisms to limit mitochondrial injury is important.
Abhijit Takawale +11 more
core +1 more source
Properties of epoxide hydrolase from the yeast Rhodotorula glutinis [PDF]
Epoxide hydrolases are ubiquitous enzymes that can be found in nearly all living organisms. Some of the enzymes play an important role in detoxifying xenobiotic and metabolic compounds.
Ariës-Kronenburg, N.A.E.
core +1 more source
New High-Throughput Screening Assays for Biocatalysis
CHIMIA, 2001 High-throughput screening for catalysis is a critical technology in all experiments aimed at modifying or creating enzymes by directed evolution, as well as for biodiversity mining for new catalysts.
Jean-Louis Reymond
doaj +2 more sources
Studies on the Biosynthesis of γ–Decalactone in Sporobolomyces odorus [PDF]
, 1990 Incubation of racemic ethyl [2,2-2H2]-(E)-3,4-epoxydecanoate and the corresponding acid with intact cells of Sporobolomyces odorus led to the formation of deuterium labeled γ-decalaetone.
Albrecht, Wolfgang, Tressl, Roland
core +1 more source
Transcriptomic and DNA Methylation Profiles of Alternative Aphid Morphs and Genotypes
Ecology and Evolution, Volume 16, Issue 5, May 2026.Graph showing the correlation between differentially expressed genes and differentially methylated genes. There is no correlation between gene expression and DNA methylation level in pea aphid polyphenism. ABSTRACT Pea aphids can develop alternative morphs when exposed to stressful conditions, showing differences between genotypes in their stress ...
Zhe Yang Yim +2 more
wiley +1 more source
An epoxide hydrolase from endophyticStreptomycesshows unique structural features and wide biocatalytic activity [PDF]
, 2020 Gabriela D. Tormet‐González +5 more
openalex +1 more source
Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases [PDF]
, 2023 Yuanguang Chen +11 more
openalex +1 more source
Vestibulotoxic properties of potential metabolites of allylnitrile [PDF]
, 2015 This study addressed the hypothesis that epoxidation of the double bond in allylnitrile mediates its vestibular toxicity, directly or after subsequent metabolism by epoxide hydrolases.
Bayona i Termens, Josep Maria +9 more
core +2 more sources
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics.
Environmental Health Perspectives, 1997 Human glutathione transferases (GSTs) are a multigene family of enzymes that are involved in the metabolism of a wide range of electrophilic compounds of both exogenous and endogenous origin.
J. Seidegård, G. Ekstrom
semanticscholar +1 more source