Results 111 to 120 of about 128,828 (279)
Association of warfarin dose with genes involved in its action and metabolism [PDF]
, 2007 We report an extensive study of variability in genes encoding proteins that are believed to be involved in the action and biotransformation of warfarin.
Mia Wadelius +73 more
core +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 16, 25 April 2026.A chemoenzymatic synthesis of (1R,2S)‐metaraminol was developed by combining gold(I)‐catalysed alkyne hydration and stereoselective biotransamination in a sequential one‐pot process. Various phenol protection strategies were considered in oxidation‐reduction sequences, providing access to enantiopure propargylic alcohols as starting materials for ...
Lorena Escot +2 more
wiley +1 more source
Citation: 'epoxide hydrolase' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10676 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources
Optimization of translation profiles enhances protein expression and solubility.
PLoS ONE, 2015 mRNA is translated with a non-uniform speed that actively coordinates co-translational folding of protein domains. Using structure-based homology we identified the structural domains in epoxide hydrolases (EHs) and introduced slow-translating codons to ...
Anne-Katrin Hess +3 more
doaj +1 more source
Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice [PDF]
, 2021 Yang Yang +8 more
openalex +1 more source
Immobilization of α-amylase from anoxybacillus sp. SK3-4 on relizyme and immobead supports [PDF]
, 2016 α-Amylase from Anoxybacillus sp. SK3-4 (ASKA) is a thermostable enzyme that produces a high level of maltose from starches. A truncated ASKA (TASKA) variant with improved expression and purification efficiency was characterized in an earlier study.
Chan, K. G. +3 more
core +2 more sources
Role of Soluble Epoxide Hydrolase in Metabolism of PUFAs in Psychiatric and Neurological Disorders
Frontiers in Pharmacology, 2019 Inflammation plays a key role in the pathogenesis of a number of psychiatric and neurological disorders. Soluble epoxide hydrolases (sEH), enzymes present in all living organisms, metabolize epoxy fatty acids (EpFAs) to corresponding 1,2-diols by the ...
Kenji Hashimoto
doaj +1 more source
Asian Journal of Pharmaceutical Research and DevelopmentEpoxyeicosatrienoic acids (EETs) have numerous cardiovascular benefits, including vasodilation, anti-inflammatory actions, and anti-migratory effects on vascular smooth muscle cells. However, sEH, an enzyme that breaks down EETs into diols, limits these benefits.
Pooja M. Sontakke +4 more
openaire +1 more source
Dihydroxy fatty acids can be used for screening autism traits in toddlers
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
Takaharu Hirai +7 more
wiley +1 more source
Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase [PDF]
, 2019 Giancarlo Abis +3 more
openalex +1 more source